Results 11 to 20 of about 171,847 (305)

Neuropathic pain [PDF]

open access: yesNature Reviews Disease Primers, 2017
Neuropathic pain is caused by a lesion or disease of the somatosensory system, including peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7-10% of the general population. Multiple causes of neuropathic pain have been described and its incidence is likely to increase owing to the ageing global population, increased incidence of ...
Colloca   +15 more
exaly   +11 more sources

Central neuropathic pain [PDF]

open access: yesNature Reviews Disease Primers, 2023
Central neuropathic pain arises from a lesion or disease of the central somatosensory nervous system such as brain injury, spinal cord injury, stroke, multiple sclerosis or related neuroinflammatory conditions. The incidence of central neuropathic pain differs based on its underlying cause.
Rosner, Jan   +6 more
openaire   +6 more sources

Neuropathic Pain

open access: yesSeminars in Neurology, 2016
Diagnosing neuropathic pain and distinguishing it from nociceptive pain can be challenging, but is essential because both forms of pain require different treatment strategies. The diagnosis of neuropathic pain is primarily based on clinical findings.
Janne, Gierthmühlen, Ralf, Baron
  +7 more sources

Localized neuropathic pain [PDF]

open access: yesGaceta Médica de México, 2023
Localized neuropathic pain (LNP) is of peripheral origin and is characterized by circumscribed areas of pain with abnormal skin sensitivity or spontaneous symptoms that are characteristic of neuropathic pain, e.g., burning pain. It should be noted that LNP is confined to a specific area no larger than a letter size sheet of paper. LNP accounts for 60 %
Ricardo, Plancarte-Sánchez   +3 more
openaire   +2 more sources

Genitofemoral neuralgia : adding to the burden of chronic vulvar pain [PDF]

open access: yes, 2015
The vulva is a particularly common locus of chronic pain with neuropathic characteristics that occurs in women of any age, though most women with neuropathic type chronic vulvar pain will remain undiagnosed even following multiple physician visits. Here,
De Muynck, Martine   +2 more
core   +2 more sources

Acute lumbar polyradiculoneuropathy as early sign of methotrexate intrathecal neurotoxicity: Case report and literature review

open access: yesClinical Case Reports, 2019
Key Clinical Message Acute paraplegia after treatment with intrathecal methotrexate requires a complete spinal cord neuroimaging as well as electrodiagnostic examination.
Carmen Montejo   +4 more
doaj   +1 more source

Neuropathic pain treatment: still a challenge

open access: yesNeurology International, 2016
Neuropathic pain (NP) is the result of a series of conditions caused by diseases or lesions to the somatosensory system. Due to the better understanding of NP pathophysiology previously unexplored therapies have been used with encouraging results.
Osvaldo J.M. Nascimento   +10 more
doaj   +1 more source

Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]

open access: yes, 2016
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina   +6 more
core   +2 more sources

Neuropathic Pain

open access: yesSeminars in Neurology, 2018
AbstractNeuropathic pain management is challenging, and typically requires a multifaceted approach. There are several treatment options, both pharmacologic and nonpharmacologic. Of the available pharmacologic agents, those with the strongest supporting evidence include tricyclic antidepressants, serotonin–norepinephrine reuptake inhibitors, and certain
Amanda, Macone, James A D, Otis
openaire   +4 more sources

Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report

open access: yesCase Reports in Medicine, 2011
A multimodal stepped care approach has been successfully applied to a patient with complex regional pain syndrome type 1 and severe intractable pain, not responding to regular neuropathic pain medication. The choice to administer drugs in creams was made
David J. Kopsky, Jan M. Keppel Hesselink
doaj   +1 more source

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