Results 21 to 30 of about 114,925 (309)

R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids [PDF]

, 2010
Background: R-flurbiprofen, one of the enantiomers of flurbiprofen racemate, is inactive with respect to cyclooxygenase inhibition, but shows analgesic properties without relevant toxicity. Its mode of action is still unclear.
Geisslinger, Gerd, Gerd Geisslinger, Ziebell Simone, Julia Metzner, Ziebell, Simone, Koch, Marco, Myrczek, Thekla, Marian, Claudiu, Dehghani, Faramarz, Rohini Kuner, Schmidt Helmut, Bechmann Ingo, Marian Claudiu, Nina Wijnvoord, Dehghani Faramarz, Philipp Bishay, Bishay, Philipp, Kuner, Rohini, Helmut Schmidt, Faramarz Dehghani, Koch Marco, Bechmann, Ingo, Metzner, Julia, Geisslinger Gerd, Irmgard Tegeder, Tegeder Irmgard, Simone Ziebell, Wijnvoord, Nina, Tegeder, Irmgard, Claudiu Marian, Kuner Rohini, Costigan, Michael, Wijnvoord Nina, Annett Häussler, Ingo Bechmann, Michael Costigan, Schmidt, Helmut, Häussler, Annett, Bechmann, Ingo Jürgen, Myrczek Thekla, Bishay Philipp, Häussler Annett, Marco Koch, Costigan Michael, Thekla Myrczek, Metzner Julia   +45 more
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NEUROPATHIC PAIN AS A CHALLENGING CLINICAL ENTITY IN OLDER ADULTS

Anti-Aging Eastern Europe, 2022
Neuropathic pain is a challenging clinical entity in older adults. Certain clinical conditions such as diabetes mellitus, cerebrovascular diseases and infections may lead to neuropathic pain in the elderly.
Ilke Coskun Benlidayi
doaj   +1 more source

Learning and memory with neuropathic pain : impact of old age and progranulin deficiency [PDF]

, 2013
Persistent neuropathic pain is a frequent consequence of peripheral nerve injuries, particularly in the elderly. Using the IntelliCage we studied if sciatic nerve injury obstructed learning and memory in young and aged mice, each in wild type and ...
Irmgard eTegeder, Vannoni, Elisabetta, Annett eHäussler, Irmgard Tegeder, Wolfer, David P., Elisabetta Vannoni, David P. Wolfer, Tegeder, Irmgard, Wolfer, David P, Elisabetta eVannoni, Annett Häussler, Häussler, Annett, Boris eAlbuquerque, Boris Albuquerque, Albuquerque, Boris, David P Wolfer, Wolfer, David Paul; id_orcid   +16 more
core   +1 more source

Walking with Neuropathic Pain: Paradoxical Shift from Burden to Support?

Case Reports in Medicine, 2015
Baclofen 5% cream can be used for the treatment of neuropathic pain. We describe an unusual case of a neuropathic pain patient with spinal cord injury.
David J. Kopsky, Jan M. Keppel Hesselink, Roberto Casale   +2 more
doaj   +1 more source

Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter? [PDF]

, 2014
The EQ-5D and Short Form (SF)12 are widely used generic health-related quality of life (HRQoL) questionnaires. They can be used to derive health utility index scores, on a scale where 0 is equivalent to death and 1 represents full health, with scores ...
Serpell, MG, Lawson, Kenny D. (R18539), Afolabi, Ebenezer, Afolabi, E, Smith, BH, Torrance, N, Bennett, MI, Dunn, KM, Smith, Blair H., Lawson, Kenny D., Smith, Blair H.; id_orcid, Dunn, Kate M., Bennett, Michael I., Lawson, Kenny, Torrance, Nicola, Serpell, Michael G., Lawson, KD   +16 more
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Central Neuropathic Pain in a Patient with Multiple Sclerosis Treated Successfully with Topical Amitriptyline

Case Reports in Medicine, 2012
Central neuropathic pain in patients with multiple sclerosis (MS) is a common debilitating symptom, which is mostly treated with tricyclic antidepressants or antiepileptics. Unfortunately, the use of these drugs is often limited due to adverse events. We
David J. Kopsky, Remko Liebregts, Jan M. Keppel Hesselink   +2 more
doaj   +1 more source

Neuropathic pain in leprosy: symptom profile characterization and comparison with neuropathic pain of other etiologies

PAIN Reports, 2018
. Introduction:. Previous studies reported a high prevalence of neuropathic pain in leprosy, being especially present in “pharmacologically cured” patients.
Irina Raicher, Patrick Raymond Nicolas Andre Ghislain Stump, Simone Bega Harnik, Rodrigo Alves de Oliveira, Rosemari Baccarelli, Lucia H.S.C. Marciano, Somei Ura, Marcos C.L. Virmond, Manoel Jacobsen Teixeira, Daniel Ciampi de Andrade   +9 more
doaj   +1 more source

Neuropathic pain and psychological morbidity in patients with treated leprosy: a cross-sectional prevalence study in Mumbai. [PDF]

PLoS Neglected Tropical Diseases, 2011
BACKGROUND: Neuropathic pain has been little studied in leprosy. We assessed the prevalence and clinical characteristics of neuropathic pain and the validity of the Douleur Neuropathique 4 questionnaire as a screening tool for neuropathic pain in ...
Estrella Lasry-Levy, Aki Hietaharju, Vivek Pai, Ramaswamy Ganapati, Andrew S C Rice, Maija Haanpää, Diana N J Lockwood   +6 more
doaj   +1 more source

Association between medically assisted detoxification and neuropathic pain [PDF]

, 2021
High-risk alcohol use is correlated with chronic pain. Chronic pain and alcohol dependence are associated with similar neurological, endocrinological and behavioural patterns, and it has been hypothesised that symptoms of neuropathic pain are exacerbated
Wilson, Iain, Thompson, Trevor
core   +1 more source

A modified score to identify and discriminate neuropathic pain: a study on the German version of the neuropathic pain symptom inventory (NPSI)

BMC Neurology, 2011
Background Neuropathic pain must be correctly diagnosed for optimal treatment. The questionnaire named Neuropathic Pain Symptom Inventory (NPSI) was developed in its original French version to evaluate the different symptoms of neuropathic pain.
Lungenhausen Margitta, Frettlöh Jule, Rogausch Jan P, Richter Helmut, Sommer Claudia, Maier Christoph   +5 more
doaj   +1 more source