Tapentadol: an effective option for the treatment of back pain [PDF]
, 2019 Back pain, including low back pain and neck pain, is the leading cause of disability worldwide. This type of pain is challenging to treat, since it presents both a nociceptive and a neuropathic component.
Coluzzi, Flaminia +3 more
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NEUROPATHIC PAIN AS A CHALLENGING CLINICAL ENTITY IN OLDER ADULTS
Anti-Aging Eastern Europe, 2022 Neuropathic pain is a challenging clinical entity in older adults. Certain clinical conditions such as diabetes mellitus, cerebrovascular diseases and infections may lead to neuropathic pain in the elderly.
Ilke Coskun Benlidayi
doaj +1 more source
Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability [PDF]
, 2018 Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum disorders, in which sensory dysfunction is increasingly recognized.
Bennett, David L. +39 more
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Walking with Neuropathic Pain: Paradoxical Shift from Burden to Support?
Case Reports in Medicine, 2015 Baclofen 5% cream can be used for the treatment of neuropathic pain. We describe an unusual case of a neuropathic pain patient with spinal cord injury.
David J. Kopsky +2 more
doaj +1 more source
Apoptotic gene expression in neuropathic pain [PDF]
, 2008 Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms ...
Annalucia Migliozzi +6 more
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Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]
, 2008 FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico +8 more
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Case Reports in Medicine, 2012 Central neuropathic pain in patients with multiple sclerosis (MS) is a common debilitating symptom, which is mostly treated with tricyclic antidepressants or antiepileptics. Unfortunately, the use of these drugs is often limited due to adverse events. We
David J. Kopsky +2 more
doaj +1 more source
PAIN Reports, 2018 . Introduction:. Previous studies reported a high prevalence of neuropathic pain in leprosy, being especially present in “pharmacologically cured” patients.
Irina Raicher +9 more
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Multicenter assessment of quantitative sensory testing (QST) for the detection of neuropathic-like pain responses using the topical capsaicin model [PDF]
, 2018 Background: The use of quantitative sensory testing (QST) in multicenter studies has been quite limited, due in part to lack of standardized procedures among centers. Aim: The aim of this study was to assess the application of the capsaicin pain model
Bushnell, M. Catherine +13 more
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Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain [PDF]
, 2017 Background: L-acetylcarnitine, a drug marketed for the treatment of chronic pain, causes analgesia by epigenetically up-regulating type-2 metabotropic glutamate (mGlu2) receptors in the spinal cord.
Battaglia, Giuseppe +10 more
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