Results 21 to 30 of about 1,094,883 (299)

A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain [PDF]

, 2015
Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK.
Harshal A. Deshmukh, Smith, Blair H., Smith, Blair H.; id_orcid, Brown, Matthew, Blair H. Smith, Meng, Weihua, Wellcome Trust Case Control Consortium 2 (WTCCC2), Palmer, Colin N. A., Palmer, Colin N.A., Wellcome Trust Case Control Consortium 2, Louise A. Donnelly, Surrogate Markers For Micro- And Macro-Vascular Hard Endpoints For Innovative Diabetes Tools (SUMMIT) Study Group, Colhoun, Helen M., Helen M. Colhoun, Donnelly, Louise A., Torrance, Nicola, Nicola Torrance, Deshmukh, Harshal A., Weihua Meng, Colin N.A. Palmer, Palmer, Colin N. A.; id_orcid   +20 more
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Neuropathic pain in endometriosis [PDF]

, 2021
Chronic pelvic pain is one of the main symptoms of endometriosis which affects 1 in 10 women of reproductive age. Historically, despite the prevalence of this condition and the impact it has on those affected, endometriosis-associated pain (EAP) has been
Coxon, Lydia
core   +1 more source

Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting. [PDF]

, 2014
Rheumatoid arthritis (RA) is an inflammatory autoimmune condition typified by systemic inflammation targeted toward synovial joints. Inhibition of proinflammatory networks by disease-modifying antirheumatic drugs, eg, methotrexate and biologic therapies,
Sofat, N, Magan, T, Vargas, M, Ahmed, S, Harrison, A   +4 more
core   +1 more source

Walking with Neuropathic Pain: Paradoxical Shift from Burden to Support?

Case Reports in Medicine, 2015
Baclofen 5% cream can be used for the treatment of neuropathic pain. We describe an unusual case of a neuropathic pain patient with spinal cord injury.
David J. Kopsky, Jan M. Keppel Hesselink, Roberto Casale   +2 more
doaj   +1 more source

Central Neuropathic Pain in a Patient with Multiple Sclerosis Treated Successfully with Topical Amitriptyline

Case Reports in Medicine, 2012
Central neuropathic pain in patients with multiple sclerosis (MS) is a common debilitating symptom, which is mostly treated with tricyclic antidepressants or antiepileptics. Unfortunately, the use of these drugs is often limited due to adverse events. We
David J. Kopsky, Remko Liebregts, Jan M. Keppel Hesselink   +2 more
doaj   +1 more source

Neuropathic pain in leprosy: symptom profile characterization and comparison with neuropathic pain of other etiologies

PAIN Reports, 2018
. Introduction:. Previous studies reported a high prevalence of neuropathic pain in leprosy, being especially present in “pharmacologically cured” patients.
Irina Raicher, Patrick Raymond Nicolas Andre Ghislain Stump, Simone Bega Harnik, Rodrigo Alves de Oliveira, Rosemari Baccarelli, Lucia H.S.C. Marciano, Somei Ura, Marcos C.L. Virmond, Manoel Jacobsen Teixeira, Daniel Ciampi de Andrade   +9 more
doaj   +1 more source

Learning and memory with neuropathic pain : impact of old age and progranulin deficiency [PDF]

, 2013
Persistent neuropathic pain is a frequent consequence of peripheral nerve injuries, particularly in the elderly. Using the IntelliCage we studied if sciatic nerve injury obstructed learning and memory in young and aged mice, each in wild type and ...
Irmgard eTegeder, Vannoni, Elisabetta, Annett eHäussler, Irmgard Tegeder, Wolfer, David P., Elisabetta Vannoni, David P. Wolfer, Tegeder, Irmgard, Wolfer, David P, Elisabetta eVannoni, Annett Häussler, Häussler, Annett, Boris eAlbuquerque, Boris Albuquerque, Albuquerque, Boris, David P Wolfer, Wolfer, David Paul; id_orcid   +16 more
core   +1 more source

R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids [PDF]

, 2010
Background: R-flurbiprofen, one of the enantiomers of flurbiprofen racemate, is inactive with respect to cyclooxygenase inhibition, but shows analgesic properties without relevant toxicity. Its mode of action is still unclear.
Geisslinger, Gerd, Gerd Geisslinger, Ziebell Simone, Julia Metzner, Ziebell, Simone, Koch, Marco, Myrczek, Thekla, Marian, Claudiu, Dehghani, Faramarz, Rohini Kuner, Schmidt Helmut, Bechmann Ingo, Marian Claudiu, Nina Wijnvoord, Dehghani Faramarz, Philipp Bishay, Bishay, Philipp, Kuner, Rohini, Helmut Schmidt, Faramarz Dehghani, Koch Marco, Bechmann, Ingo, Metzner, Julia, Geisslinger Gerd, Irmgard Tegeder, Tegeder Irmgard, Simone Ziebell, Wijnvoord, Nina, Tegeder, Irmgard, Claudiu Marian, Kuner Rohini, Costigan, Michael, Wijnvoord Nina, Annett Häussler, Ingo Bechmann, Michael Costigan, Schmidt, Helmut, Häussler, Annett, Bechmann, Ingo Jürgen, Myrczek Thekla, Bishay Philipp, Häussler Annett, Marco Koch, Costigan Michael, Thekla Myrczek, Metzner Julia   +45 more
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The prevalence, characteristics and morbidity of neuropathic pain in AIDS patients, prior to the use of HAART, at the Kalafong Hospital HIV clinic, Pretoria [PDF]

, 2008
Includes bibliographical references (leaves 49-56).Neuropathic pain, of which a distal sensory polyneuropathy (DSP) is the most frequent cause, is a common problem in patients with HIV infection and AIDS. The researcher is concerned that neuropathic pain
Hitchcock, Sonia Anne
core   +1 more source

NEUROPATHIC PAIN AS A CHALLENGING CLINICAL ENTITY IN OLDER ADULTS

Anti-Aging Eastern Europe, 2022
Neuropathic pain is a challenging clinical entity in older adults. Certain clinical conditions such as diabetes mellitus, cerebrovascular diseases and infections may lead to neuropathic pain in the elderly.
Ilke Coskun Benlidayi
doaj   +1 more source