Results 281 to 290 of about 180,995 (352)

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

open access: yesCell Proliferation, EarlyView.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng   +4 more
wiley   +1 more source

Statin therapy and neuropathy in type 1 diabetes: A cross‐sectional study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Dyslipidaemia contributes to the pathogenesis of diabetic peripheral neuropathy (DPN). While statins improve cardiovascular outcomes in diabetes, their potential neurotoxic effects remain debated. This study examined the impact of statin use on neuropathy in type 1 diabetes mellitus (T1DM). Materials and Methods Participants with T1DM (n =
Raabya Pasha   +9 more
wiley   +1 more source

Artificial Intelligence Chatbots as Virtual Patients in Dental Education: A Constructivist Approach to Classroom Implementation

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Introduction Advances in artificial intelligence (AI) have led to new possibilities for AI role‐play in classroom settings, where generative pre‐trained transformers (GPTs) and chatbots can potentially simulate interactions with patients.
Bree Jones   +2 more
wiley   +1 more source

Association of maternal epilepsy with perinatal outcomes, and an exploration of prenatal antiseizure medication: A population‐based retrospective cohort study

open access: yesEpilepsia, EarlyView.
Abstract Objective(s) Pregnancy in women with epilepsy is associated with adverse perinatal outcomes, but debate remains as to role of epilepsy or of prenatal antiseizure medication (ASM), or both. We aimed to investigate the association between maternal epilepsy and perinatal outcomes, and to explore the role of prenatal ASM exposure.
Paolo Pieirino Mazzone   +5 more
wiley   +1 more source

MicroRNA-Based Delivery Systems for Chronic Neuropathic Pain Treatment in Dorsal Root Ganglion. [PDF]

open access: yesPharmaceutics
Jackson S   +4 more
europepmc   +1 more source

Peripheral blood mononuclear cell secretome from patients with autoimmune encephalitis promotes seizures in vitro

open access: yesEpilepsia, EarlyView.
Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti   +14 more
wiley   +1 more source

Neuro-Nutritional Approach to Neuropathic Pain Management: A Critical Review. [PDF]

open access: yesNutrients
Cominelli G   +5 more
europepmc   +1 more source

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