Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients
Annals of Neurology, EarlyView.Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer +14 more
wiley +1 more source
Comparative analysis of chronic neuropathic pain and pain assessment in companion animals and humans
Frontiers in Veterinary ScienceChronic neuropathic pain is underdiagnosed in companion animals. This paper will review the definition of pain and how classification and grading of neuropathic pain can be applied from human to veterinary medicine to increase the recognition of and the ...
Rell L. Parker
doaj +1 more source
Cross-sectional comparison of cannabis use in adults with neuropathic versus non-neuropathic pain
Frontiers in Pain ResearchIntroductionCannabis has been decriminalized by many states and shows promise in treating both neuropathic and non-neuropathic pain through its interaction with the endocannabinoid system and anti-inflammatory effects.
Carl Joshua P. Laroya +7 more
doaj +1 more source
Loss of neurons from laminas I-III of the spinal dorsal horn is not required for development of tactile allodynia in the spared nerve injury model of neuropathic pain [PDF]
, 2005 It has been proposed that death of inhibitory interneurons in the dorsal horn contributes to the neuropathic pain that follows partial nerve injury. In this study, we have used two approaches to test whether there is neuronal death in the dorsal horn in ...
Polgar, Erika +3 more
core +1 more source
A neuropathic pain scale is effective in identifying neuropathic pain
American Journal of Translational ResearchTo explore the application value of a Neuropathic Pain Questionnaire (NPQ) in screening for neuropathic pain (NP).Using a prospective study approach, patients with chronic pain treated and hospitalized in Quanzhou First Hospital between September 2020 and December 2023 were chosen as study subjects. Participants were screened using NPQ and then divided
Jianying, Zhou +3 more
openaire +2 more sources
Neurophysiological and histopathological evaluation of small fiber pathways as diagnostic characterization of neuropathic pain and autonom dysfunction syndromes [PDF]
, 2012 This manuscript is made up of two individual not related articles about peripheral neuropathic pain syndrome. The first article reports the effect on pain relief in patients with peripheral neuropathic pain after brachial plexus lesions or distal ...
Devigli, Grazia, Devigili, Grazia
core
Spinal cord stimulation for neuropathic pain: current perspectives [PDF]
, 2014 Tilman Wolter Interdisciplinary Pain Centre, University Hospital Freiburg, Freiburg, Germany Abstract: Neuropathic pain constitutes a significant portion of chronic pain.
Wolter, Tilman, Wolter T
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Motor cortex electric stimulation for the treatment of neuropathic pain
Arquivos de Neuro-Psiquiatria, 2010 OBJECTIVE: Motor cortex stimulation (MCS) is considered to be an effective treatment for chronic neuropathic pain. The aim of the present study was to assess the efficacy of MCS for treating neuropathic pain.
Walter J. Fagundes-Pereyra +6 more
doaj +1 more source
Neuropathic Pain in Females with Fibromyalgia Syndrome: The Role of Obesity
, 2023 Objective:This study aimed to assess the impact of obesity on neuropathic pain, fibromyalgia symptoms, and quality of life in female patients diagnosed with fibromyalgia syndrome.Materials and Methods:This study enrolled 40 normal-weight and 40 obese ...
Meltem Yener Mankır +7 more
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Opioids for neuropathic pain [PDF]
, 2006 The use of opioids for neuropathic pain remains controversial. Studies have been small, have yielded equivocal results, and have not established the long-term risk-benefit ratio of this treatment.To assess the efficacy and safety of opioid agonists for the treatment of neuropathic pain.We searched the Cochrane Central Register of Controlled Trials (2nd
E, Eisenberg, E, McNicol, D B, Carr
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