Results 61 to 70 of about 1,094,883 (299)

Botulinum Toxin for Central Neuropathic Pain

open access: yesToxins, 2018
Botulinum toxin (BTX) is widely used to treat muscle spasticity by acting on motor neurons. Recently, studies of the effects of BTX on sensory nerves have been reported and several studies have been conducted to evaluate its effects on peripheral and ...
Jihye Park, Myung Eun Chung
doaj   +1 more source

Peripheral Neuropathic Pain: From Experimental Models to Potential Therapeutic Targets in Dorsal Root Ganglion Neurons

open access: yesCells, 2020
Neuropathic pain exerts a global burden caused by the lesions in the somatosensory nerve system, including the central and peripheral nervous systems. The mechanisms of nerve injury-induced neuropathic pain involve multiple mechanisms, various signaling ...
Ti-Yen Yeh   +5 more
doaj   +1 more source

Pressure ulcer related pain in community populations: a prevalence survey. [PDF]

open access: yes, 2014
BACKGROUND: Pressure ulcers are costly to the healthcare provider and can have a major impact on patient's quality of life. One of the most distressing symptoms reported is pain.
McGinnis, Elizabeth   +33 more
core   +2 more sources

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong   +17 more
wiley   +1 more source

Neuropathic pain: targeting the melatonin MT2 receptor

open access: yesSouth African Family Practice, 2016
Neuropathic pain affects a large proportion of the population and reduces a person’s ability to perform optimally. In South Africa, there are a host of factors that hinder the correct diagnosis and treatment of neuropathic pain.
N. Smith, H. Ismail, N. Schellack
doaj   +1 more source

Prevalence of chronic pain in Libya before and after the uprising of 17 February 2011. [PDF]

open access: yes, 2013
Two questionnaires were translated into Arabic and culturally adapted to measure chronic pain and neuropathic pain in the general population in Derna, Libya (1, 2), and then in a country-wide survey.
Tashani, OA, Osama A. Tashani
core   +1 more source

Treatment of Neuropathic Pain [PDF]

open access: yesSeminars in Neurology, 2010
Neuropathic pain is a common symptom associated with peripheral neuropathy and can be as or more disabling than the effects of nerve damage from the neuropathy. Though treatment of the underlying pathophysiology causing neuropathies may not be possible, treatment of neuropathic pain is.
openaire   +2 more sources

Differential diagnosis of neuropathic pain

open access: yesНеврология, нейропсихиатрия, психосоматика, 2015
Neuropathic pain is an acute or chronic pain caused by damage to or dysfunction of the peripheral and/or central nervous system. Neuropathic pain is a direct sequel of damage to or disease of the somatosensory nervous system.
Yu. N. Bykov, A. N. Kalyagin
doaj   +1 more source

Topical Treatments and Their Molecular/Cellular Mechanisms in Patients with Peripheral Neuropathic Pain—Narrative Review

open access: yesPharmaceutics, 2021
Neuropathic pain in humans results from an injury or disease of the somatosensory nervous system at the peripheral or central level. Despite the considerable progress in pain management methods made to date, peripheral neuropathic pain significantly ...
Magdalena Kocot-Kępska   +6 more
doaj   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

open access: yesAdvanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou   +8 more
wiley   +1 more source

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