Results 71 to 80 of about 1,094,883 (299)
Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study.
PLoS ONE, 2018 The underlying mechanisms of neuropathic pain remain to be elucidated. Basic animal research has suggested that lysophosphatidic acids, which are bioactive lipids produced by autotaxin from lysophosphatidylcholine, may play key roles in the initiation ...
Ken Kuwajima +10 more
doaj +1 more source
Pharmacologic Aspect of Neuropathic Pain [PDF]
, 2015 Neuropathic pain is pain arising from nerve damage to the conductive pathways of pain (ranging from nociceptors to post central gyrus). Neuropathic pain can be caused by 1) Carcinomas, 2) Trap/compressive, 3) Congenital, 4) Immunomediated, 5) Infection,
Mutiawati, Endang +3 more
core +2 more sources
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr +7 more
wiley +1 more source
Treadmill running on neuropathic pain: via modulation of neuroinflammation
Frontiers in Molecular NeuroscienceNeuropathic pain is a type of chronic pain caused by an injury or somatosensory nervous system disease. Drugs and exercise could effectively relieve neuropathic pain, but no treatment can completely stop neuropathic pain. The integration of exercise into
Wei-Chun He +7 more
doaj +1 more source
Statins and Neuropathic Pain: A Narrative Review
Pain and Therapy, 2020 The frequently prescribed drug class of statins have pleiotropic effects and have been implicated in neuropathic pain syndromes. This narrative review examines studies of statin-induced neuropathic pain which to date have been conducted only in animal ...
Joseph V. Pergolizzi +5 more
doaj +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen +5 more
wiley +1 more source
Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain. [PDF]
, 2020 OBJECTIVES: Little is known about the epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. We aimed to describe prevalence, characteristics and clinical course of low back-related leg pain patients with and
Dunn
core +1 more source
Annals of Neurology, EarlyView.Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato +7 more
wiley +1 more source
Gabapentin in neuropathic pain syndromes: a randomised, double-blind, placebo-controlled trial
, 2002 A double-blind, randomised, placebo-controlled 8-week study was conducted to evaluate the efficacy and safety of gabapentin in the treatment of neuropathic pain, using doses up to 2400 mg/day.
Neuropathic Pain Study Grp +2 more
core +1 more source
, 2022 Objective:In this study, our aimed was to investigate the frequency of neuropathic pain in women diagnosed with postmenopausal osteoporosis (OP), its effects on sleep quality, quality of life, depression and the relationship between these findings ...
Gülseren Dost Sürücü +2 more
core +1 more source