Do SARS-CoV-2 Variants Differ in Their Neuropathogenicity? [PDF]
mBio, 2023 Neurological complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are a huge societal problem. Although the neuropathogenicity of SARS-CoV-2 is not yet fully understood, there is evidence that SARS-CoV-2 ...
Lisa Bauer, Debby van Riel
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Amino acid changes accumulated in the fusion protein allow neuropathogenic measles viruses to use a broad repertoire of host factors for cell fusion triggering [PDF]
Journal of VirologyMeasles virus (MeV), an enveloped RNA virus belonging to the genus Morbillivirus of the family Paramyxoviridae, is the causative agent of measles, an acute febrile illness with skin rash. MeV has two types of envelope glycoproteins: the hemagglutinin (H)
Yuichi Hirai +3 more
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Multiple Receptors Involved in Invasion and Neuropathogenicity of Canine Distemper Virus: A Review [PDF]
Viruses, 2022 The canine distemper virus (CDV) is a morbillivirus that infects a broad range of terrestrial carnivores, predominantly canines, and is associated with high mortality.
Jianjun Zhao, Yanrong Ren
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A Point Mutation in a Herpesvirus Co-Determines Neuropathogenicity and Viral Shedding [PDF]
Viruses, 2017 A point mutation in the DNA polymerase gene in equine herpesvirus type 1 (EHV-1) is one determinant for the development of neurological disease in horses.
Mathias Franz +4 more
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Breaking Latent Infection: How ORF37/38-Deletion Mutants Offer New Hope against EHV-1 Neuropathogenicity [PDF]
VirusesEquid alphaherpesvirus 1 (EHV-1) has been linked to the emergence of neurological disorders, with the horse racing industry experiencing significant impacts from outbreaks of equine herpesvirus myeloencephalopathy (EHM).
Yue Hu +7 more
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Neuro-Ophthalmic Dengue Infection: A Case Report with a Multiple Body Site Sampling Strategy and Review of Laboratory Data [PDF]
VirusesDengue neurological disease is an uncommon yet severe complication of dengue infection. It can manifest as encephalitis, encephalopathy, neuro-ophthalmic complications, or neuromuscular disorders.
Grace I. Butel-Simoes +11 more
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A Recombinant System and Reporter Viruses for Papiine Alphaherpesvirus 2 [PDF]
Viruses, 2022 Primate simplex viruses, including Herpes simplex viruses 1 and 2, form a group of closely related herpesviruses, which establish latent infections in neurons of their respective host species.
Abdul Rahman Siregar +7 more
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Conserved non-coding RNA motifs influence the neuropathogenicity of Simbuviruses: Molecular dissection in the Schmallenberg virus model [PDF]
PLoS PathogensThe Simbu serogroup, part of the Peribunyaviridae family, includes arboviruses associated with febrile illnesses in humans and fetal congenital malformations due to viral neurotropism in ruminants.
Laura Bonil +7 more
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Langat Virus Biology and Infection. [PDF]
Rev Med VirolABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Klestova Z +3 more
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Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection [PDF]
Viruses, 2018 Zika virus (ZIKV) causes no-to-mild symptoms or severe neurological disorders. To investigate the importance of viral and host genetic variations in determining ZIKV infection outcomes, we created three full-length infectious cDNA clones as bacterial ...
Sang-Im Yun +8 more
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