Results 31 to 40 of about 805 (153)

Development of Polioencephalomyelitis in Cesarean-Derived Colostrum-Deprived Pigs Following Experimental Inoculation with Either Teschovirus A Serotype 2 or Serotype 11

open access: yesViruses, 2017
Teschovirus encephalomyelitis is a sporadic disease associated with Teschovirus A (PTV) serotype 1 and, less frequently, other serotypes. In recent years, the number of cases submitted to the Iowa State University Veterinary Diagnostic Laboratory with a ...
Franco Matias Ferreyra   +9 more
doaj   +1 more source

Measles Fusion Machinery Is Dysregulated in Neuropathogenic Variants [PDF]

open access: yesmBio, 2015
ABSTRACT Paramyxoviruses, including the human pathogen measles virus (MV), enter host cells by fusing their viral envelope with the target cell membrane. This fusion process is driven by the concerted actions of the two viral envelope glycoproteins, the receptor binding protein (hemagglutinin [H]) and the fusion (F) protein.
Jurgens, Eric M   +6 more
openaire   +4 more sources

Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection

open access: yesViruses, 2018
Zika virus (ZIKV) causes no-to-mild symptoms or severe neurological disorders. To investigate the importance of viral and host genetic variations in determining ZIKV infection outcomes, we created three full-length infectious cDNA clones as bacterial ...
Sang-Im Yun   +8 more
doaj   +1 more source

Outbreak of neuropathogenic equid herpesvirus 1 causing abortions in Yili horses of Zhaosu, North Xinjiang, China

open access: yesBMC Veterinary Research, 2022
Background EHV-1 is one of the most serious viral pathogens that frequently cause abortion in horses around the world. However, so far, relatively little information is available on EHV-1 infections as they occur in China.
Panpan Tong   +11 more
doaj   +1 more source

Neuropathogenic and non-neuropathogenic EHV-1 strains induce the accumulation of hyperphosphorylated Tau in primary murine neurons

open access: yesActa virologica, 2020
Equid herpesvirus 1 (EHV-1) causes respiratory disease, abortion and neurological disorders in horses. Similarly, to other alphaherpesviruses, EHV-1 is neurotropic and establishes latency in the neurons of its natural host. Despite the fact that many studies have been devoted to the pathogenesis of various clinical forms of EHV-1 infection, mechanisms ...
J, Cymerys   +5 more
openaire   +3 more sources

Human Foamy Virus: An Underestimated Neuropathogen?

open access: yesBrain Pathology, 1991
Human foamy virus (HFV) is a recently characterized retrovirus which was originally isolated from patients with various neoplastic and degenerative diseases. However, until today it has not been possible to identify HFV as the causative agent of any disease and little is known about its prevalence in human populations.
A, Aguzzi   +4 more
openaire   +2 more sources

Modelling West Nile Virus and Usutu Virus Pathogenicity in Human Neural Stem Cells

open access: yesViruses, 2020
West Nile virus (WNV) and Usutu virus (USUV) are genetically related neurotropic mosquito-borne flaviviruses, which frequently co-circulate in nature. Despite USUV seeming to be less pathogenic for humans than WNV, the clinical manifestations induced by ...
Silvia Riccetti   +5 more
doaj   +1 more source

Tissue-specific expansion of Zika virus isogenic variants drive disease pathogenesisResearch in context

open access: yesEBioMedicine, 2023
Summary: Background: The Asian lineage Zika virus (ZIKV) emerged as a public health emergency in 2016 causing severe neurological pathologies with no apparent historical correlate to the mild, disease-causing innocuous member of the mosquito-borne ...
Kitti Wing Ki Chan   +5 more
doaj   +1 more source

Differences in neuroinvasion and protective innate immune pathways between encephalitic California Serogroup orthobunyaviruses.

open access: yesPLoS Pathogens, 2022
The California serogroup (CSG) of Orthobunyaviruses comprises several members capable of causing neuroinvasive disease in humans, including La Crosse orthobunyavirus (LACV), Jamestown Canyon orthobunyavirus (JCV), and Inkoo orthobunyavirus (INKV ...
Alyssa B Evans   +2 more
doaj   +1 more source

Identification of a Novel Neuropathogenic Theiler's Murine Encephalomyelitis Virus [PDF]

open access: yesJournal of Virology, 2011
ABSTRACT Theiler's murine encephalitis viruses (TMEV) are divided into two subgroups based on their neurovirulence. Persistent strains resemble Theiler's original viruses (referred to as the TO subgroup), which largely induce a subclinical polioencephalomyelitis during the acute phase of the disease and can persist in the spinal cord of ...
Buckwalter, Matthew R   +14 more
openaire   +3 more sources

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