Results 11 to 20 of about 1,609 (181)

Cross-Section of Neurological Manifestations Among SARS-CoV-2 Omicron Subvariants—Single-Center Study [PDF]

Brain Sciences
Background/Objectives: The Omicron variant of SARS-CoV-2 is undergoing constant mutation. New strains vary in neuropathogenicity and the neurological spectrum of disease.
Justyna Jachman-Kapułka, Aleksander Zińczuk, Krzysztof Simon, Marta Rorat   +3 more
doaj   +2 more sources

Interaction of the Hemagglutinin Stalk Region with Cell Adhesion Molecule (CADM) 1 and CADM2 Mediates the Spread between Neurons and Neuropathogenicity of Measles Virus with a Hyperfusogenic Fusion Protein. [PDF]

J Virol, 2023
Takemoto R, Hirai Y, Watanabe S, Harada H, Suzuki T, Hashiguchi T, Yanagi Y, Shirogane Y.   +7 more
europepmc   +3 more sources

The neuropathogenesis of highly pathogenic avian influenza H5Nx viruses in mammalian species including humans. [PDF]

Trends Neurosci, 2023
Circulation of highly pathogenic avian influenza (HPAI) H5Nx viruses of the A/Goose/Guangdong/1/96 lineage in birds regularly causes infections of mammals, including humans.
Bauer L, Benavides FFW, Veldhuis Kroeze EJB, de Wit E, van Riel D.   +4 more
europepmc   +4 more sources

Fibroblast growth factor receptor inhibitors mitigate the neuropathogenicity of Borrelia burgdorferi or its remnants ex vivo [PDF]

Frontiers in Immunology
In previous studies, we showed that fibroblast growth factor receptors (FGFRs) contribute to inflammatory mediator output from primary rhesus microglia in response to live Borrelia burgdorferi. We also demonstrated that non-viable B.
Geetha Parthasarathy
doaj   +2 more sources

Combined mutations in nonstructural protein 14, envelope, and membrane proteins mitigate the neuropathogenicity of SARS-CoV-2 Omicron BA.1 in K18-hACE2 mice [PDF]

mSphere
We previously reported that mutations outside the spike protein play a role in the attenuation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 variant in human ACE2 transgenic mice (K18-hACE2).
Kotou Sangare, Shufeng Liu, Prabhuanand Selvaraj, Charles B. Stauft, Matthew F. Starost, Tony T. Wang   +5 more
doaj   +2 more sources

Epidemiological and Clinical Characteristics of the Enterovirus D68 Outbreak in Spain in 2024 [PDF]

J Med Virol
ABSTRACT Enterovirus D68 (EV‐D68) is a significant cause of respiratory and neurological disease worldwide. In 2024, Spain experienced its largest recorded EV‐D68 outbreak, accounting for 37.4% of all typed EV (294/892). This study describes the epidemiological, clinical, and phylogenetic features of EV‐D68 infections.
Camacho J, García‐Ibáñez N, Fernández‐García M, Biya Y, Ruiz de Pedro E, Gutiérrez A, Nieto M, Ruiz‐García M, Pastor‐Fajardo M, Lagarejos E, de Leonardo Simón C, Navascués A, Moreno‐Docón A, Gozalo‐Marguello M, Berengua C, Antequera P, Huéscar‐Pascual M, Calvo C, Cabrerizo M.   +18 more
europepmc   +2 more sources

Collective fusion activity determines neurotropism of an en bloc transmitted enveloped virus. [PDF]

Sci Adv, 2023
麻疹（はしか）ウイルスが「協力」して脳炎を引き起こす仕組みを解明 --新規治療薬の開発やウイルス共通の進化メカニズム解明に期待--. 京都大学プレスリリース. 2023-01-30.Measles virus (MeV), which is usually non-neurotropic, sometimes persists in the brain and causes subacute sclerosing panencephalitis (SSPE) several years after ...
Shirogane Y, Harada H, Hirai Y, Takemoto R, Suzuki T, Hashiguchi T, Yanagi Y.   +6 more
europepmc   +3 more sources

SARS-CoV-2 Omicron Variants Show Attenuated Neurovirulence Compared with the Wild-Type Strain in Elderly Human Brain Spheroids [PDF]

Research
Infection with severe acute respiratory syndrome coronavirus 2 Omicron variants still causes neurological complications in elderly individuals. However, whether and how aging brains are affected by Omicron variants in terms of neuroinvasiveness and ...
Weikang Chen, Xiaobing Jiang, Wei Liang, Haojie Bai, Mingze Xu, Zhe Liu, Lina Yi, Yanming Liu, Yanxia Huang, Yongxin Zhang, Lixia Xu, Baoshu Xie, Nu Zhang, Jun Yu, Jing Lu, Haipeng Xiao, Xiaoxing Li   +16 more
doaj   +2 more sources

Identification of neuropathogenic Varicellovirus equidalpha1 as a potential cause of respiratory disease outbreaks among horses in North Xinjiang, China, from 2021-2023 [PDF]

BMC Veterinary Research
Background Varicellovirus equidalpha1 (formerly Equid alphaherpesvirus 1, EqAHV-1) is among the most important viruses responsible for respiratory disease outbreaks among horses throughout the world.
Panpan Tong, Enhui Yang, Bin Liu, Shuyao tian, Youtu Suo, JuanJuan Pan, Yueyi Dang, Nuerlan Palidan, Chenyang Jia, Ling Kuang, Jinxin Xie   +10 more
doaj   +2 more sources

Role of bovine herpesvirus type 5 (BoHV-5) in diseases of cattle. Recent findings on BoHV-5 association with genital disease [PDF]

Open Veterinary Journal, 2012
Bovine herpesvirus type 5 (BoHV-5) belongs to the family Herpesviridae, subfamily Alphaherpesvirinae, genus Varicellovirus. This virus is a major causative agent of non-suppurative meningoencephalitis in young cattle. It was first isolated in 1962 from a
S.E. Pérez, M.S. Marin, P.A. Favier
doaj   +6 more sources