Results 21 to 30 of about 1,609 (181)

Translocator protein (TSPO)-PET as diagnostic and monitoring tool in COVID-19 related MRI-negative brainstem encephalitis: a case report. [PDF]

J Neurol, 2023
Wischmann J, Bartos LM, Brendel M, Albert NL, Forbrig R, Straube A, Masouris I.   +6 more
europepmc   +3 more sources

Genomic analysis and replication kinetics of the closely related EHV-1 neuropathogenic 21P40 and abortigenic 97P70 strains. [PDF]

Vet Res
Mohamed E, Zarak I, Vereecke N, Theuns S, Laval K, Nauwynck H.   +5 more
europepmc   +3 more sources

Attenuation of the neuropathogenic equine herpesvirus type 1 strain Ab4p in hamsters by a single amino acid mutation (D752N) in viral DNA polymerase ORF30. [PDF]

J Vet Med Sci
Nishimura F, Fukushi N, Sakai H, Fukushi H.   +3 more
europepmc   +3 more sources

Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models. [PDF]

PLoS ONE, 2016
Saffold virus (SAFV), a picornavirus, is occasionally detected in children with acute flaccid paralysis, meningitis, and cerebellitis; however, the neuropathogenicity of SAFV remains undetermined.The virulence of two clinical isolates of SAFV type 3 ...
Osamu Kotani, Asif Naeem, Tadaki Suzuki, Naoko Iwata-Yoshikawa, Yuko Sato, Noriko Nakajima, Takushi Hosomi, Hiroyuki Tsukagoshi, Kunihisa Kozawa, Hideki Hasegawa, Fumihiro Taguchi, Hiroyuki Shimizu, Noriyo Nagata   +12 more
doaj   +1 more source

Neuropathogenicity of non-viable Borrelia burgdorferi ex vivo

Scientific Reports, 2022
Even after appropriate treatment, a proportion of Lyme disease patients suffer from a constellation of symptoms, collectively called Post-Treatment Lyme Disease Syndrome (PTLDS).
Geetha Parthasarathy, Shiva Kumar Goud Gadila   +1 more
doaj   +1 more source

A point mutation in a herpesvirus polymerase determines neuropathogenicity. [PDF]

PLoS Pathogens, 2007
Infection with equid herpesvirus type 1 (EHV-1) leads to respiratory disease, abortion, and neurologic disorders in horses. Molecular epidemiology studies have demonstrated that a single nucleotide polymorphism resulting in an amino acid variation of the
Laura B Goodman, Arianna Loregian, Gillian A Perkins, Josie Nugent, Elizabeth L Buckles, Beatrice Mercorelli, Julia H Kydd, Giorgio Palù, Ken C Smith, Nikolaus Osterrieder, Nicholas Davis-Poynter   +10 more
doaj   +1 more source

Necroptosis of neuronal cells is related to the neuropathology of tick-borne encephalitis

Virus Research, 2022
Tick-borne encephalitis virus (TBEV) is a zoonotic virus that causes tick-borne encephalitis (TBE) in humans. Infections of Sapporo-17-Io1 (Sapporo) and Oshima 5-10 (Oshima) TBEV strains showed different pathogenic effects in mice.
Dai Tsujino, Kentaro Yoshii, Misa Kajiyama, Yuji Takahashi, Naoya Maekawa, Hiroaki Kariwa, Shintaro Kobayashi   +6 more
doaj   +1 more source

Changes in transmission of Enterovirus D68 (EV-D68) in England inferred from seroprevalence data

eLife, 2023
The factors leading to the global emergence of Enterovirus D68 (EV-D68) in 2014 as a cause of acute flaccid myelitis (AFM) in children are unknown. To investigate potential changes in virus transmissibility or population susceptibility, we measured the ...
Margarita Pons-Salort, Ben Lambert, Everlyn Kamau, Richard Pebody, Heli Harvala, Peter Simmonds, Nicholas C Grassly   +6 more
doaj   +1 more source

Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus

Nature Communications, 2023
Mammalian orthoreovirus (reovirus) infects most mammals and is associated with celiac disease in humans. In mice, reovirus infects the intestine and disseminates systemically to cause serotype-specific patterns of disease in the brain.
Pengcheng Shang, Joshua D. Simpson, Gwen M. Taylor, Danica M. Sutherland, Olivia L. Welsh, Pavithra Aravamudhan, Rita Dos Santos Natividade, Kristina Schwab, Joshua J. Michel, Amanda C. Poholek, Yijen Wu, Dhivyaa Rajasundaram, Melanie Koehler, David Alsteens, Terence S. Dermody   +14 more
doaj   +1 more source

Study of BBB Dysregulation in Neuropathogenicity Using Integrative Human Model of Blood–Brain Barrier

Frontiers in Cellular Neuroscience, 2022
The blood–brain barrier (BBB) is a cellular and physical barrier with a crucial role in homeostasis of the brain extracellular environment. It controls the imports of nutrients to the brain and exports toxins and pathogens.
Coraly Simöes Da Gama, Mélanie Morin-Brureau   +1 more
doaj   +1 more source