Molecular characterization of Brazilian equid herpesvirus type 1 strains based on neuropathogenicity markers [PDF]
, 2015 Ênio Mori +8 more
core +2 more sources
T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus
eLife, 2022 JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a life-threatening brain disease in immunocompromised patients. Inherited and acquired T cell deficiencies are associated with PML.
Matthew D Lauver +6 more
doaj +1 more source
Neuropathophysiological potential of Guillain-Barré syndrome anti-ganglioside-complex antibodies at mouse motor nerve terminals [PDF]
, 2011 Objectives: Anti-ganglioside antibodies are present in approximately half of Guillain–Barré syndrome (GBS) patients. Recently, it has been shown that a considerable proportion of these patients has serum antibodies against antigenic epitopes formed by a
Goodfellow +22 more
core +1 more source
Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]
, 2019 Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid +7 more
core +1 more source
Oncolytic herpes simplex virus-based strategies: toward a breakthrough in glioblastoma therapy [PDF]
, 2014 Oncolytic viruses (OV) are a class of antitumor agents that selectively kill tumor cells while sparing normal cells. Oncolytic herpes simplex virus (oHSV) has been investigated in clinical trials for patients with the malignant brain tumor glioblastoma ...
Ning, Jianfang, Wakimoto, Hiroaki
core +3 more sources
Study of Usutu virus neuropathogenicity in mice and human cellular models.
PLoS Neglected Tropical Diseases, 2020 Usutu virus (USUV), an African mosquito-borne flavivirus closely related to West Nile virus, was first isolated in South Africa in 1959. USUV emerged in Europe two decades ago, causing notably massive mortality in Eurasian blackbirds.
Marion Clé +17 more
doaj +1 more source
Viruses, 2017 Teschovirus encephalomyelitis is a sporadic disease associated with Teschovirus A (PTV) serotype 1 and, less frequently, other serotypes. In recent years, the number of cases submitted to the Iowa State University Veterinary Diagnostic Laboratory with a ...
Franco Matias Ferreyra +9 more
doaj +1 more source
Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors [PDF]
, 2013 BACKGROUND: Alzheimer’s disease (AD) is characterized by progressive memory loss and impaired cognitive function. Early-onset familial forms of the disease (FAD) are caused by inheritance of mutant genes encoding presenilin 1 (PS1) variants.
Karthikeyan Veeraraghavalu +3 more
core +1 more source
BMC Veterinary Research, 2022 Background EHV-1 is one of the most serious viral pathogens that frequently cause abortion in horses around the world. However, so far, relatively little information is available on EHV-1 infections as they occur in China.
Panpan Tong +11 more
doaj +1 more source
Clinical observations and management of a severe equine herpesvirus type 1 outbreak with abortion and encephalomyelitis [PDF]
, 2013 Latent equine herpesvirus type 1 (EHV-1) infection is common in horse populations worldwide and estimated to reach a prevalence nearing 90% in some areas.
Bleul, Ulrich +4 more
core +2 more sources