Results 81 to 90 of about 1,031 (173)

Mortality Risk Following Delirium in Older Inpatients: A Systematic Review and Meta‐Analysis

Worldviews on Evidence-Based Nursing, Volume 22, Issue 3, June 2025.
ABSTRACT Background The onset of delirium in older inpatients is associated with worse outcomes, including longer length of hospital stay, loss of functionality, loss of cognitive function, sleep disorders, increased polypharmacy, higher rates of adverse effects, and mortality.
Pilar Pérez‐Ros, Noelia Plaza‐Ortega, Francisco Miguel Martínez‐Arnau   +2 more
wiley   +1 more source

Human Endogenous Retrovirus K in Astrocytes Is Altered in Parkinson's Disease

Movement Disorders, Volume 40, Issue 4, Page 683-692, April 2025.
Abstract Background Parkinson's disease (PD) is the most common neurodegenerative movement disease. Human endogenous retroviruses (HERVs) are proviral remnants of ancient retroviral infection of germ cells that now constitute about 8% of the human genome.
YuHong Fu, Gabrielle L. Adler, Priscilla Youssef, Katherine Phan, Glenda M. Halliday, Nicolas Dzamko, Woojin Scott Kim   +6 more
wiley   +1 more source

Subacute Sclerosing Panencephalitis: Impact on Public Health, Current Insights, and Future Perspectives

Brain and Behavior, Volume 15, Issue 2, February 2025.
Subacute sclerosing panencephalitis (SSPE) is a severe complication of measles that demands global attention. The only way to eradicate measles and prevent its complications is through widespread immunization and increased public awareness. ABSTRACT Background Subacute Sclerosing Panencephalitis (SSPE) is a rare complication of the measles infection ...
Zainab Mubbashir, Zoaib Habib Tharwani, Tilyan Kambar, Sadia Munawar, Ozem Raphael, Iman Siddiqui, Syeda Ayesha Nadeem, Ayesha Amir, Amina Ahmed, Muhammad Daim Bin Zafar, Muhammad Umair Anjum, Muhammad Hasanain, Abdullah Malikzai   +12 more
wiley   +1 more source

Genetically Stable Poliovirus Vectors Activate Dendritic Cells and Prime Antitumor CD8 T Cell Immunity

, 2019
Viruses naturally engage innate immunity, induce antigen presentation, and mediate CD8 T cell priming against foreign antigens. Polioviruses can provide a context optimal for generating antigen-specific CD8 T cells, as they have natural tropism for ...
Mosaheb, Mohammad Mubeen
core   +1 more source

Genetic evidence for serum amyloid P component as a drug target in neurodegenerative disorders

Open Biology
The mechanisms responsible for neuronal death causing cognitive loss in Alzheimer's disease (AD) and many other dementias are not known. Serum amyloid P component (SAP) is a constitutive plasma protein, which is cytotoxic for cerebral neurones and also ...
A. Floriaan Schmidt, Chris Finan, Sandesh Chopade, Stephan Ellmerich, Martin N. Rossor, Aroon D. Hingorani, Mark B. Pepys   +6 more
doaj   +1 more source

Comparison of clinical variables and outcome of 2 natural equine herpesvirus myeloencephalopathy outbreaks induced by equine herpesvirus‐1 A2254/N752 strain in sport horses

Journal of Veterinary Internal Medicine, Volume 39, Issue 1, January/February 2025.
Abstract Background Understanding of equine herpesvirus‐1 (EHV‐1) myeloencephalopathy (EHM) is complicated by disparities among studies. Objective Compare clinical findings and outcome in horses involved in 2 recent EHM outbreaks. Animals Twenty‐five and 10 horses affected during 2 natural EHM outbreaks were admitted to a veterinary teaching hospital ...
María de la Cuesta‐Torrado, Ana Velloso Alvarez, José Miguel Cárdenas‐Rebollo, Patricia Neira‐Egea, Valentina Vitale, Juan Cuervo‐Arango   +5 more
wiley   +1 more source

Experimental infection of calves with a gI, gE, US9 negative bovine herpesvirus type 5

, 2005
In this work, a role for the genes encoding glycoproteins I (gI) and E (gE) and the US9 protein of bovine herpesvirus type 5 (BHV-5) in neuropathogenicity and reactivation of latent infections was examined.
Rijsewijk, F.A.M., Franco, A.C., Hubner, S.O., Roehe, P.M., Oliveira, A.P.   +4 more
core   +1 more source

West-Nile virus-induced neuropathogenicity is strain specific

, 2012
International ...
Coulpier, Muriel
core   +4 more sources

Role of bovine herpesvirus type 5 (BoHV-5) in diseases of cattle. Recent findings on BoHV-5 association with genital disease [PDF]

Open Veterinary Journal, 2012
Bovine herpesvirus type 5 (BoHV-5) belongs to the family Herpesviridae, subfamily Alphaherpesvirinae, genus Varicellovirus. This virus is a major causative agent of non-suppurative meningoencephalitis in young cattle. It was first isolated in 1962 from a
S.E. Pérez, M.S. Marin, P.A. Favier
doaj  

The increased prevalence of neuropathogenic strains of EHV-1 in equine abortions

Veterinary Microbiology, 2010
A panel of 426 archived EHV-1 isolates collected (1951-2006) from equine abortions was analyzed using a real-time Taq-Man((R)) allelic discrimination PCR assay. Based on previous findings, isolates possessing adenine at nucleotide position 2254 (A(2254)) in ORF30 were classified as having a non-neuropathogenic genotype and those with guanine at 2254 (G(
Smith, Kathryn L., Allen, George P., Branscum, Adam J., Cook, R. Frank, Vickers, Mary L., Timoney, Peter J., Balasuriya, Udeni B.R.   +6 more
openaire   +2 more sources