Results 61 to 70 of about 1,091 (176)

Übertragungswege neuropathogener Erreger – mögliche Mechanismen der Neuroinvasion

open access: yesDer Nervenarzt, 2023
Despite natural protective barriers, many human pathogens can penetrate the nervous system. The pathogens have developed sophisticated mechanisms to overturn the privileged immune status of the nervous system. The central nervous system (CNS) has natural barriers and immunological protective mechanisms, such as the blood-brain barrier (BBB) and the ...
openaire   +2 more sources

New insights on the neuropathogenicity of West Nile virus [PDF]

open access: yesFEMS Microbiology Letters, 2004
West Nile virus (WNV) is a mosquito-borne disease that emerged in North America where it caused in 2002 the largest arboviral meningoencephalitis outbreak ever recorded in this area. The viral variant responsible of this outbreak has been found to share 99.7% identity over the entire genome with the viral variant that caused the epizootic in Israel in ...
Pierre-Emmanuel Ceccaldi   +2 more
openaire   +1 more source

Molecular characterisation of equid alphaherpesvirus 1 strains isolated from aborted fetuses in Poland

open access: yesVirology Journal, 2018
Background Equid alphaherpesvirus 1 (EHV-1) is one of the main infectious causative agents of abortion in mares and can also be associated with stillbirth, neonatal foal death, rhinopneumonitis in young horses and a neurological disorder called equine ...
Anna Karolina Matczuk   +3 more
doaj   +1 more source

Nitric oxide debilitates the neuropathogenic schistosome Trichobilharzia regenti in mice, partly by inhibiting its vital peptidases

open access: yesParasites & Vectors, 2020
Background Avian schistosomes, the causative agents of human cercarial dermatitis (or swimmer’s itch), die in mammals but the mechanisms responsible for parasite elimination are unknown.
Tomáš Macháček   +5 more
doaj   +1 more source

Autoimmunity to Collagen XVII (BP180‐Ag2) in Pemphigoid Associated With Parkinson’s Disease

open access: yesCase Reports in Dermatological Medicine, Volume 2026, Issue 1, 2026.
The association between Parkinson’s disease and autoimmune disease is rare; in our population, there is 1 case per 10,000 inhabitants. Bullous pemphigoid has a much lower incidence, and consequently, the association of Parkinson’s disease and bullous pemphigoid is rarer.
Ricardo Cid-Puente   +6 more
wiley   +1 more source

Redox‐Dependent Activation of Matrix Metalloproteinases Regulates Influenza A Virus Replication in Neuronal Cells

open access: yesInternational Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Influenza A virus (IAV) is a major respiratory pathogen with the potential to invade the central nervous system (CNS), leading to neurological complications. However, the mechanisms underlying IAV neurotropism and its impact on neuronal cells remain poorly understood.
Carla Prezioso   +8 more
wiley   +1 more source

Extracellular matrix in the CNS induced by neuropathogenic viral infection [PDF]

open access: yesNeuropathology, 2017
During the early phase of infection with an extremely neurovirulent murine coronavirus, cl‐2, the ER‐TR7 antigen (ERag)‐positive fibers (ERfibs) associated with laminin and collagen III show a rapid increase in expression levels in the meninges, followed by an appearance of the antigens in the ventricle and brain parenchyma.
Rihito Watanabe, Masatoshi Kakizaki
openaire   +2 more sources

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

open access: yesAdvanced Functional Materials, Volume 35, Issue 50, December 9, 2025.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput   +5 more
wiley   +1 more source

Characterization of strain PTV-2 USA/IA65463/2014 and strain PTV-11 USA/IA09592/2013 of Teschovirus A: Experimental inoculation, distribution of nucleic acids and development of Teschovirus encephalomyelitis [PDF]

open access: yes, 2001
Teschovirus A (previously Porcine teschovirus; PTV) is the etiologic agent of Teschovirus encephalomyelitis (TE). Historically, PTV-1 has been recognized as one of the most pathogenic serotypes, although other serotypes have been described to cause TE ...
Matias Ferreyra, Franco   +1 more
core   +1 more source

Infectious Triggers and Immune Dynamics in Guillain–Barré Syndrome: Revisiting Campylobacter jejuni and the Silent Role of Haemophilus influenzae

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
Schematic representation of the gut‐brain axis and microbial triggers in Guillain–Barré Syndrome. Post‐infectious immune responses, particularly through molecular mimicry by pathogens, such as Campylobacter jejuni and Haemophilus influenzae, lead to demyelination and subsequent neuromuscular paralysis.
Aswathi Ramesh   +5 more
wiley   +1 more source

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