Results 111 to 120 of about 174,921 (327)

Neural Dedifferentiation in Relation to Risk for Alzheimer\u27s Disease [PDF]

open access: yes, 2010
Functional magnetic resonance imaging (fMRI) research indicates that as an individual\u27s age increases, the task-related spatial extent of neural activation increases.
Hantke, Nathan C.
core   +1 more source

An algorithm for seizure detection in rodents

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky   +9 more
wiley   +1 more source

Unlocking the Link of Twin Profiles of Plasma Fatty Acids and Genetic Risk and Their Interactions With Incident Dementia

open access: yesFood Frontiers, EarlyView.
Plasma MUFAs, n‐6 PUFAs (particularly LA), and n‐3 PUFAs (particularly non‐DHA n‐3 PUFAs) were found to be inversely associated with dementia risk. The interactions with APOE genotypes and genetic risk score were also observed, as well as the mediation of serum biomarkers. The study highlights the importance of refining plasma fatty acid profiles based
Hao Ye   +11 more
wiley   +1 more source

Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12

open access: yesGlia, EarlyView.
Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz   +9 more
wiley   +1 more source

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

open access: yesIbrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

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