Results 21 to 30 of about 114,817 (184)

Humans correctly assign emotional valence of rat vocalizations

Frontiers in Psychology
Emotions are signalled among conspecifics but also to other species to facilitate ethologically meaningful responses towards external and internal cues.
Eduard Maier, Eduard Maier, Shimpei Ishiyama, Shimpei Ishiyama, Valery Grinevich, Valery Grinevich, Michael Brecht, Michael Brecht, Michael Brecht   +8 more
doaj   +1 more source

Vasoactive Intestinal Peptide Deficiency Is Associated With Altered Gut Microbiota Communities in Male and Female C57BL/6 Mice

Frontiers in Microbiology, 2019
Vasoactive intestinal peptide (VIP) is crucial for gastrointestinal tract (GIT) health. VIP sustains GIT homeostasis through maintenance of the intestinal epithelial barrier and acts as a potent anti-inflammatory mediator that contributes to gut ...
Manpreet Bains, Caleb Laney, Annie E. Wolfe, Megan Orr, James A. Waschek, Aaron C. Ericsson, Glenn P. Dorsam   +6 more
doaj   +1 more source

An FMRFamide Neuropeptide in Cuttlefish Sepia pharaonis: Identification, Characterization, and Potential Function

Molecules, 2020
Neuropeptides are released by neurons that are involved in a wide range of brain functions, such as food intake, metabolism, reproduction, and learning and memory.
Yang Zhu, Lian-lian Sun, Jun-hong Wu, Hui-hui Liu, Li-bing Zheng, Zhen-ming Lü, Chang-feng Chi   +6 more
doaj   +1 more source

The neurobiology of ticklishness

Neuroscience Research
Ticklishness is an idiosyncratic form of touch observed in multiple animal species, including humans. Although commonly regarded as trivial, it involves complex neurobiological mechanisms and diverse behavioral phenomena observed across species.
Shimpei Ishiyama
doaj   +1 more source

An opioid-like system regulating feeding behavior in C. elegans

eLife, 2015
Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115
Mi Cheong Cheong, Alexander B Artyukhin, Young-Jai You, Leon Avery   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortex

Nature Communications
The hypothalamic neuropeptide oxytocin is best known for its prosocial behavioral effects. However, the precise anatomical and cellular targets for oxytocin in the cortex during social behavior remain elusive.
Stephanie Schimmer, Alan Kania, Arthur Lefevre, Konstantinos Afordakos, Kai-Yi Wang, Julia Lebedeva, Andrei Rozov, Androniki Raftogianni, Rishika Tiwari, Shai Netser, Ana Zovko, Huma Shaheen, Jonas Schimmer, Ryan Patwell, Clémence Denis, Valentin Grelot, Hugues Petitjean, Lan Geng, Dimitri Hefter, Arjen Boender, Yuval Podpecan, Franziska Schommer, Tim Schubert, Anna Sanetra, Aleksandra Trenk, Anna Gugula, René Hurlemann, Shlomo Wagner, Yulong Li, Ferdinand Althammer, Anna Blasiak, Sarah Melzer, Hannah Monyer, Alexandre Charlet, Marina Eliava, Valery Grinevich   +35 more
doaj   +1 more source

Genome Editing Reveals Idiosyncrasy of CNGA2 Ion Channel-Directed Antibody Immunoreactivity Toward Oxytocin

Frontiers in Cell and Developmental Biology, 2018
Presynaptic cGMP-gated ion (CNG) channels positively or negatively modulate neurotransmitter secretion as well as the strength of synaptic transmission. Zebrafish cGMP-gated ion channel, CNGA2a (a.k.a.
Janna Blechman, Savani Anbalagan, Gary G. Matthews, Gil Levkowitz   +3 more
doaj   +1 more source

The endogenous neuropeptide calcitonin gene-related peptide after spontaneous subarachnoid hemorrhage–A potential psychoactive prognostic serum biomarker of pain-associated neuropsychological symptoms

Frontiers in Neurology, 2022
BackgroundThe pronociceptive neuromediator calcitonin gene-related peptide (CGRP) is associated with pain transmission and modulation. After spontaneous subarachnoid hemorrhage (sSAH), the vasodilatory CGRP is excessively released into cerebrospinal ...
Elisabeth Bründl, Martin Proescholdt, Eva-Maria Störr, Petra Schödel, Sylvia Bele, Florian Zeman, Christoph Hohenberger, Martin Kieninger, Nils Ole Schmidt, Karl-Michael Schebesch   +9 more
doaj   +1 more source