Results 31 to 40 of about 88,878 (295)

Genome Editing Reveals Idiosyncrasy of CNGA2 Ion Channel-Directed Antibody Immunoreactivity Toward Oxytocin

open access: yesFrontiers in Cell and Developmental Biology, 2018
Presynaptic cGMP-gated ion (CNG) channels positively or negatively modulate neurotransmitter secretion as well as the strength of synaptic transmission. Zebrafish cGMP-gated ion channel, CNGA2a (a.k.a.
Janna Blechman   +3 more
doaj   +1 more source

Evolution of Orexin Neuropeptide System: Structure and Function

open access: yesFrontiers in Neuroscience, 2020
Orexins are hypothalamic neuropeptides that were initially identified in the rat brain as endogenous ligands for an (previously) orphan G-protein-coupled receptor (GPCR).
Shingo Soya, Takeshi Sakurai
doaj   +1 more source

Overexpression of the Gene Encoding Neurosecretory Protein GL Precursor Prevents Excessive Fat Accumulation in the Adipose Tissue of Mice Fed a Long-Term High-Fat Diet

open access: yesMolecules, 2021
We previously identified a novel small hypothalamic protein, neurosecretory protein GL (NPGL), which induces feeding behavior and fat accumulation in rodents depending on their diet.
Keisuke Fukumura   +5 more
doaj   +1 more source

Magnesium-based implants: Beyond fixators

open access: yesJournal of Orthopaedic Translation, 2017
The mystery behind magnesium-induced bone formation is revealed by linking the neuropeptide(s) from sensory nerves with the osteogenic differentiation of stem cells in the periosteum.
Xiaodan Chen
doaj   +1 more source

The Neuropeptide Cortistatin Alleviates Neuropathic Pain in Experimental Models of Peripheral Nerve Injury

open access: yesPharmaceutics, 2021
Neuropathic pain is one of the most severe forms of chronic pain caused by the direct injury of the somatosensory system. The current drugs for treating neuropathies have limited efficacies or show important side effects, and the development of ...
Clara P. Falo   +9 more
doaj   +1 more source

A Comparative Study of Two Blast-Induced Traumatic Brain Injury Models: Changes in Monoamine and Galanin Systems Following Single and Repeated Exposure

open access: yesFrontiers in Neurology, 2018
Repeated mild blast-induced traumatic brain injury (rmbTBI), caused by recurrent exposure to low levels of explosive blast, is a significant concern for military health systems. However, the pathobiology of rmbTBI is currently poorly understood.
Lizan Kawa   +7 more
doaj   +1 more source

Morphology and Chemical Messenger Regulation of Echinoderm Muscles

open access: yesBiology, 2023
The muscular systems of echinoderms play important roles in various physiological and behavioral processes, including feeding, reproduction, movement, respiration, and excretion.
Huachen Liu, Muyan Chen
doaj   +1 more source

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets

open access: yesAdvanced Science, EarlyView.
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu   +10 more
wiley   +1 more source

Peptide Cotransmitters as Dynamic, Intrinsic Modulators of Network Activity

open access: yesFrontiers in Neural Circuits, 2018
Neurons can contain both neuropeptides and “classic” small molecule transmitters. Much progress has been made in studies designed to determine the functional significance of this arrangement in experiments conducted in invertebrates and in the vertebrate
Elizabeth C. Cropper   +4 more
doaj   +1 more source

Social Interaction Is Less Rewarding in Adult Female than in Male Mice

open access: yesBrain Sciences, 2023
(1) Background: Positive social relationships are essential for mental and physical health. However, not all individuals experience social interaction as a rewarding activity.
Anna E. Granza   +5 more
doaj   +1 more source

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