Results 231 to 240 of about 74,318 (299)

Reduced Mechanical Tactile Stimulation Under Space Microgravity Affects Synaptic Signaling and Contributes to Neuromuscular Aging in Caenorhabditis elegans

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Microgravity (μG) reduces mechanical tactile stimulation in Caenorhabditis elegans, causing neuromuscular decline, altered gene expression, synaptic defects, and accelerated aging phenotypes. The gentle‐touch mechanoreceptor MEC‐4 mediates μG‐induced body length reduction and extracellular matrix gene downregulation.
Atsushi Higashitani, Je‐Hyun Moon, Jong‐In Hwang, Nahoko Higashitani, Toko Hashizume, Ahmad Aisha Abu, Kazuki Ooizumi, Ibuki Sazuka, Yoshimitsu Hashizume, Masumi Umehara, Alfredo V. Alcantara Jr, Ban‐seok Kim, Timothy Etheridge, Nathaniel J. Szewczyk, Takaaki Abe, Jin I. Lee, Akira Higashibata   +16 more
wiley   +1 more source

Neuropeptide Y Y2 receptors in acute and chronic pain and itch. [PDF]

Neuropeptides
Basu P, Taylor BK.
europepmc   +1 more source

Proanthocyanidin‐Rich Cranberry Extract Lowers Glycemia in Established Obesity by Delaying Glucose Absorption

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Schematic summary of the metabolic effects and proposed mechanisms of action of proanthocyanidin‐rich cranberry extract (PRCE) supplementation in mice with established diet‐induced obesity housed under thermoneutral (30°C) or cold‐exposed (10°C) conditions.
Sarra Beji, Mathilde Mouchiroud, Laura Tribouillard, Bernie Efole, Lia Perazza, Léa Favereaux, Audrey Poirier, Wandy Idris, Yves Gélinas, Thibault V. Varin, Carole Rovère, Fernando Forato Anhê, Frédéric Picard, Mathieu Laplante, André Marette, Andréanne Michaud, Alexandre Caron   +16 more
wiley   +1 more source

Mechanism and Intervention of the NPY1R/CREB Signaling Axis in Regulating Inflammatory Response in Aged Ovarian Granulosa Cells and Ovarian Senescence

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Aging‐associated upregulation of NPY1R drives p‐CREB activation, triggering inflammation, mitochondrial dysfunction, and extracellular matrix imbalance to promote ovarian senescence. Pharmacological inhibition of NPY1R with BIBO 3304 restores ovarian homeostasis, highlighting a therapeutic strategy for reproductive aging. ABSTRACT Ovarian senescence is
Junnan Fang, Chaoying Wang, Shuaishuai Guo, Yiping Zhang, Yang Zhang, Huihui Wang, Yue Kong, Haixia Jin, Lin Qi, Yan Liu, Zhaoting Wu, Fuli Zhang, Shuang Wen, Xiaopeng Wang, Guang Yang, Guidong Yao   +15 more
wiley   +1 more source

Neuropeptide Y and Pain: Insights from Brain Research. [PDF]

ACS Pharmacol Transl Sci
Nelson TS, Allen HN, Khanna R.
europepmc   +1 more source

Targeted CRISPR approach reveals an essential role for neuropeptide Y receptor Y5 in Ewing sarcoma extrapulmonary metastasis. [PDF]

Oncogene
Adnani M, Hong SH, Galli S, Mahajan A, Lu C, Abualsaud N, Biermann T, Li Y, Rivera A, Sebsebie BS, Caprio L, Kuwahara L, Krawczyk E, Tilan JU, Lee Y, Rodriguez O, Wang H, Jin L, Regan M, de Assis S, Albanese C, Pack SD, Cavalli LR, Kitlinska J.   +23 more
europepmc   +1 more source

Exosomes from mesenchymal stem/stromal cells and their therapeutic role in osteoarthritic pain

Journal of Experimental Orthopaedics, Volume 13, Issue 3, July 2026.
Dimitrios Kouroupis, Stanislava Jergova, Jacqueline Sagen, Thomas M. Best   +3 more
wiley   +1 more source

The Role of Neuropeptide Y in the Pathogenesis of Alzheimer's Disease: Diagnostic Significance and Neuroprotective Functions. [PDF]

Neurol Int
Shapovalova K, Zorkina Y, Abramova O, Andryushchenko A, Chekhonin V, Kostyuk G.   +5 more
europepmc   +1 more source

De novo expression of neuropeptide Y in sensory neurons does not contribute to peripheral neuropathic pain. [PDF]

J Pain
Cooper AH, Nie AA, Hedden NS, Herzog H, Taylor BK.   +4 more
europepmc   +1 more source

Neuropeptide Y

Zukowska-Grojec, Zofia, Karwatowska-Prokopczuk, Ewa, Rose, Wesley, Rone, Janice, Movafagh, Sharareh, Ji, Hong, Yeh, Yunyun, Chen, Wen-Tien, Kleinman, Hynda K., Grouzmann, Eric, Grant, Derrick S.   +10 more
openaire   +1 more source