Results 61 to 70 of about 9,276,761 (294)

Intranasal neuropeptide Y is most effective in some aspects of acute stress compared to melatonin, oxytocin and orexin

Frontiers in Pharmacology, 2022
Objectives: In the current study, we compared the effects of a single intranasal administration of clomipramine with effects of four neuropeptides, melatonin, oxytocin, orexin, and neuropeptide Y, to compare them in an acute stress model.Methods: The ...
Eugene Zubkov, Olga Abramova, Olga Abramova, Yana Zorkina, Yana Zorkina, Aleksandra Ochneva, Aleksandra Ochneva, Valeria Ushakova, Valeria Ushakova, Valeria Ushakova, Anna Morozova, Anna Morozova, Olga Gurina, Alexander Majouga, Vladimir Chekhonin, Vladimir Chekhonin   +15 more
doaj   +1 more source

Contrast Agent Clearance Dynamics and Diffusion in the Mouse Brain After Ventricular Administration

Advanced Science, EarlyView.
Schematic representation of contrast agent clearance by convective bulk flow from the ventricular spaces to the subarachnoid space on the ventral aspect of the brain, or by diffusion into the parenchyma across the pia‐glia or through the semi‐permeable ependyma. Abstract Fluid and solute exchange between cerebrospinal fluid (CSF) spaces and the central
Yann Decker, Andreas Müller, Steven T. Proulx   +2 more
wiley   +1 more source

Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures

Neurobiology of Disease, 2012
We recently demonstrated that recombinant adeno-associated viral vector-induced hippocampal overexpression of neuropeptide Y receptor, Y2, exerts a seizure-suppressant effect in kindling and kainate-induced models of epilepsy in rats.
Casper R. Gøtzsche, Litsa Nikitidou, Andreas T. Sørensen, Mikkel V. Olesen, Gunnar Sørensen, Søren H.O. Christiansen, Mikael Ängehagen, David P.D. Woldbye, Merab Kokaia   +8 more
doaj  

Relationship between the Production Traits and three Candidate Genes in the Prolactin’s In/Del×In/Del Population of Silkie Fowl

The Journal of Poultry Science, 2014
Silkie fowl are very famous in China and Japan, however the egg production rate of the Silkie fowl is very low because of broodiness. Authors have examined the polymorphisms of the 5′-flanking region of the prolactin gene in Taihe Silkie fowl and ...
MD. Mijanur Rahman, Riho Matsuda, Tomoe Matsuda, Yuki Nishiyama, Kosuke Jozaki, Kajio Anann, Yasuhiko Wada   +6 more
doaj   +1 more source

Amino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis

Advanced Science, EarlyView.
This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo, Kexin Tong, Yeting Gan, Min Tang, Yuguo Niu, Kan Liu, Shihong Ni, Shangming Wu, Xiaoxue Jiang, Haizhou Jiang, Fei Xiao, Shanghai Chen, Wei Lv, Xiaoying Li, Feixiang Yuan, Feifan Guo   +15 more
wiley   +1 more source

Heat Stress Biomarker Amino Acids and Neuropeptide Afford Thermotolerance in Chicks

The Journal of Poultry Science, 2019
With global warming, heat stress is becoming a pressing concern worldwide. In chickens, heat stress reduces food intake and growth, and increases body temperature and stress responses.
Vishwajit S. Chowdhury
doaj   +1 more source

Neuropeptide Y: complete amino acid sequence of the brain peptide.

Proceedings of the National Academy of Sciences of the United States of America, 1982
The amino acid sequence of neuropeptide Y, a 36-residue peptide recently isolated from porcine brain, has been determined by using high performance liquid chromatography for separation of its tryptic and chymotryptic fragments and subsequent sequence ...
K. Tatemoto
semanticscholar   +1 more source

Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain

Advanced Science, EarlyView.
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang, Xiuru Ji, Yu Sun, Han Wang, Ting Wang, Tao Luo, Yanyong Cheng, Jia Yan, Dalong Ni, Hong Jiang   +9 more
wiley   +1 more source

Discovery of novel representatives of bilaterian neuropeptide families and reconstruction of neuropeptide precursor evolution in ophiuroid echinoderms [PDF]

Open Biology, 2017
Neuropeptides are a diverse class of intercellular signalling molecules that mediate neuronal regulation of many physiological and behavioural processes.
Meet Zandawala, Ismail Moghul, Luis Alfonso Yañez Guerra, Jérôme Delroisse, Nikara Abylkassimova, Andrew F. Hugall, Timothy D. O'Hara, Maurice R. Elphick   +7 more
doaj   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source