Results 211 to 220 of about 212,465 (393)

Downregulation of the NPY-Y1R system in Grpr neurons results in mechanical and chemical hyperknesis in chronic itch

open access: yesNeurobiology of Disease
Chronic itch remains a clinically challenging condition with limited therapeutic efficacy, posing a significant burden on patients' quality of life. Despite its prevalence, the underlying neural mechanisms remain poorly understood.
Danqing Dai   +7 more
doaj  

Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone   +28 more
wiley   +1 more source

Mediators of epilepsy risk after traumatic brain injury: A 20‐year U.S. veteran cohort study

open access: yesEpilepsia, Volume 66, Issue 4, Page 1177-1186, April 2025.
Abstract Objective Traumatic brain injury (TBI) is a significant risk factor for epilepsy, but little work has explored whether risk of epilepsy after TBI may operate through intermediary mechanisms. The objective of this study was to statistically screen for potentially mediating effects among 64 comorbidities for epilepsy risk following TBI among ...
Shashank Vadlamani   +7 more
wiley   +1 more source

Increased expression of the neuropeptide Y receptor Y1 gene in the medial amygdala of transgenic mice induced by long‐term treatment with progesterone or allopregnanolone [PDF]

open access: bronze, 2001
Gianna Ferrara   +6 more
openalex   +1 more source

Enhancement of neurogenesis and cognition through intranasal co-delivery of galanin receptor 2 (GALR2) and neuropeptide Y receptor 1 (NPY1R) agonists: a potential pharmacological strategy for cognitive dysfunctions. [PDF]

open access: yesBehav Brain Funct
Sánchez-Varo R   +10 more
europepmc   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez   +2 more
wiley   +1 more source

Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes. [PDF]

open access: yesCell Signal, 2014
Gimenez LE   +4 more
europepmc   +1 more source

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