Results 211 to 220 of about 87,108 (308)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

The Association Between Disordered Eating and Sleep in Non‐Clinical Populations—A Systematic Review and Meta‐Analysis

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep and disordered eating behaviours may be linked through physiological and psychological mechanisms; yet, no review has systematically investigated the relationship between different sleep indicators and disordered eating behaviours and cognitions outside a clinical context.
Marie‐Christine Opitz, Nora Trompeter, Francisco Diego Rabelo‐da‐Ponte, Michelle Carroll, Kyle Buchan, Giulia Gaggioni, Sarah Moody, Sylvane Desrivières, Nadia Micali, Ulrike Schmidt, Helen Sharpe, EDIFY Consortium, Ulrike Schmidt, Helen Sharpe, Karina Allen, Heike Bartel, Iain Campbell, Sylvane Desrivières, Richard Dobson, Amos Folarin, Tara French, John Kelly, Umairah Malik, Nadia Micali, Sneha Raman, Zulqarnain Rashid, Janet Treasure, Callum Bryson, Daire Douglas, Amelia Hemmings, Başak İnce Çağlar, Carina Kuehne, Sarah Moody, Marie‐Christine Opitz, Tamsin Parnell, Fiona Stephens, Nora Trompeter, Jessica Wilkins, Alice Bromell, Grace Davis, Cameron Eadie, Beck Heslop, Isabella Malvisi, Katie Mckenzie, Emma Scott, Chris Sims, Tallulah Street, Andreia Tavares‐Semedo, Eleanor Wilkinson, Lucz Zocek   +49 more
wiley   +1 more source

Effect of Centrally Administered Neuropeptide Y and α-Melanocyte-stimulating Hormone on Water Intake in Chicks. [PDF]

J Poult Sci
Dialoke NG, Murata K, Zhang Y, Taniguchi Y, Hinomoto SI, Takegaki J, Saneyasu T, Honda K.   +7 more
europepmc   +1 more source

Corticotropin‐Releasing Hormone (CRH) in Murine Narcolepsy: What Do Genetic and Immune Models Tell Us?

Journal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou, S. Melzi, A. L. Morel, B. Georges, T. E. Scammell, G. J. Lammers, R. Fronczek, C. Peyron   +7 more
wiley   +1 more source

Olfactory inputs to appetite neurons in the hypothalamus. [PDF]

Proc Natl Acad Sci U S A
Kuang D, Hanchate NK, Lee CY, Heck A, Ye X, Erdenebileg M, Mehta C, Hassan MM, Setty M, Buck LB.   +9 more
europepmc   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Journal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads, Megan H. Hagenauer, Jinglin Xiong, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Elizabeth Flandreau, Stanley Watson Jr., Huda Akil   +8 more
wiley   +1 more source

The pathway-independent positive allosteric modulator C1 allows for the identification of active Y₄ receptor relevant positions. [PDF]

Cell Mol Life Sci
Schüß C, Vu O, Pelczyk T, Schubert M, Du Y, Stichel J, Weaver CD, Meiler J, Beck-Sickinger AG.   +8 more
europepmc   +1 more source

Neuropeptide Y receptor gene expression in the primate amygdala predicts anxious temperament and brain metabolism. [PDF]

Biol Psychiatry, 2014
Roseboom PH, Nanda SA, Fox AS, Oler JA, Shackman AJ, Shelton SE, Davidson RJ, Kalin NH.   +7 more
europepmc   +1 more source

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

Neurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao, Yan‐lin Liu, Xiao‐mei Wang, Kai Cheng, Qing‐yu Tu, Fei Dai, Xi‐bing Yang   +6 more
wiley   +1 more source

Fine-Tuning of the Neuropeptide Y1 G Protein-Coupled Receptor by the Tryptophan^6.48 "Toggle Switch". [PDF]

J Am Chem Soc
Voitel M, Pankonin M, Vogel A, Leitner K, Kaiser A, Huster D, Hildebrand PW, Smith AA.   +7 more
europepmc   +1 more source