Neuropeptides as regulators of bone metabolism: from molecular mechanisms to traditional Chinese medicine intervention strategies. [PDF]
Front PharmacolLin Q +9 more
europepmc +1 more source
MRI‐based surrogates of brain clearance in narcolepsy type 1
Journal of Sleep Research, EarlyView.Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese +6 more
wiley +1 more source
Neuropeptide Y in first-episode schizophrenia: is there any sex differences in the pathogeneses of schizophrenia? [PDF]
Front PsychiatrySong JQ +5 more
europepmc +1 more source
Neurogenomic landscape associated with status‐dependent cooperative behaviour
Molecular Ecology, EarlyView.Abstract The neurogenomic mechanisms mediating male–male reproductive cooperative behaviours remain unknown. We leveraged extensive transcriptomic and behavioural data on a neotropical bird species (Pipra filicauda) that performs cooperative courtship displays to understand these mechanisms.
Peri E. Bolton +6 more
wiley +1 more source
Enteric neuropathy and the vagus nerve: Therapeutic implications
Neurogastroenterology &Motility, EarlyView.Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source
The human colon: Evidence for degenerative changes during aging and the physiological consequences
Neurogastroenterology &Motility, EarlyView.Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley +1 more source
Targeting the central and peripheral nervous system to regulate bone homeostasis: mechanisms and potential therapies. [PDF]
Mil Med ResLiang TZ +7 more
europepmc +1 more source
Gastric and sacral electrical stimulation for motility disorders—A clinical perspective
Neurogastroenterology &Motility, EarlyView.Abstract Background Electrical stimulation of the gut has been investigated in recent decades with a view to treating various gastro‐intestinal motility disorders including, among others, gastric electrical stimulation to relieve nausea and vomiting associated with gastroparesis and sacral neuromodulation to treat fecal incontinence and/or constipation.
Charlotte Desprez +2 more
wiley +1 more source
Smoking, Obesity, and Post-Cessation Weight Gain: Neurobiological Intersection and Treatment Recommendations. [PDF]
J Multidiscip HealthcGolden A, Davis JM.
europepmc +1 more source
Central mechanisms of emesis: A role for GDF15
Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.Abstract Background Nausea and emesis are ubiquitously reported medical conditions and often present as treatment side effects along with polymorbidities contributing to detrimental life‐threatening outcomes, such as poor nutrition, lower quality of life, and unfavorable patient prognosis.
Tito Borner +2 more
wiley +1 more source