Results 301 to 310 of about 212,465 (393)

Cell type-specific driver lines targeting the <i>Drosophila</i> central complex and their use to investigate neuropeptide expression and sleep regulation. [PDF]

Elife
Wolff T, Eddison M, Chen N, Nern A, Sundaramurthi P, Sitaraman D, Rubin GM.   +6 more
europepmc   +1 more source

Evidence‐based review and frontiers of migraine therapy

Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Cyclic vomiting syndrome (CVS) is identified as one of the “episodic syndromes that may be associated with migraine,” along with benign paroxysmal torticollis, benign paroxysmal vertigo, and abdominal migraine. It has been proposed that CVS and migraine may share pathophysiologic mechanisms of hypothalamic activation and altered ...
Kaitlin A. Greene, Amy A. Gelfand, Larry Charleston IV   +2 more
wiley   +1 more source

Neural influences in colorectal cancer progression and therapeutic strategies. [PDF]

Int J Colorectal Dis
Zeng Z, Cai S, Ye C, Li T, Tian Y, Liu E, Cai J, Yuan X, Yang H, Liang Q, Li K, Peng C.   +11 more
europepmc   +1 more source

Endocannabinoid signaling in stress, nausea, and vomiting

Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Classical antiemetics that target the serotonin system may not be effective in treating certain nausea and vomiting conditions like cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS). As a result, there is a need for better therapies to manage the symptoms of these disorders, including nausea, vomiting, and ...
Marieka V. DeVuono, Thangam Venkatesan, Cecilia J. Hillard   +2 more
wiley   +1 more source

G_zESTY as an optimized cell-based assay for initial steps in GPCR deorphanization. [PDF]

Nat Commun
Franchini L, Porter JJ, Lueck JD, Orlandi C.   +3 more
europepmc   +1 more source

Decoding Gastric Reflexes: The Role of Mechanosensitive Enteric Neurons in Stomach Motility

Neurogastroenterology &Motility, EarlyView.
ABSTRACT This review focuses on mechanosensitive enteric neurons (MEN) in the guinea pig stomach and their roles in gastric motor reflex pathways. The guinea pig model is advantageous for studying gastric physiology, as its stomach structure and function closely resemble those of humans. Gastric motility involves distinct functional regions: the fundus
Gemma Mazzuoli‐Weber, Sophia Mayr, Kristin Elfers   +2 more
wiley   +1 more source

Sensory plasticity caused by up-down regulation encodes the information of short-term learning and memory. [PDF]

iScience
Wang PZ, Ge MH, Su P, Wu PP, Wang L, Zhu W, Li R, Liu H, Wu JJ, Xu Y, Zhao JL, Li SJ, Wang Y, Chen LM, Wu TH, Wu ZX.   +15 more
europepmc   +1 more source

Sex Specific Effects of Environmental Toxin‐Derived Alpha Synuclein on Enteric Neuronal‐Epithelial Interactions

Neurogastroenterology &Motility, EarlyView.
Sex‐specific alterations in intestinal neuronal‐epithelial interactions between calcitonin gene related peptide (CGRP) and goblet cells secondary to elevated enteric alpha synuclein (aSyn) potentially contribute to gastrointestinal dysfunction in Parkinson's Disease (PD). ABSTRACT Background Parkinson's Disease (PD) is a neurodegenerative disorder with
Hayley N. Templeton, Alexis T. Ehrlich, Luke A. Schwerdtfeger, Julietta A. Sheng, Ronald B. Tjalkens, Stuart A. Tobet   +5 more
wiley   +1 more source

GPCRs in hypothalamic neurons and their roles in controlling food intake and metabolism. [PDF]

Front Mol Neurosci
Qiu T, Fu O.
europepmc   +1 more source

Age‐dependent reduction in voltage‐gated inward sodium current and Scn8a gene expression in murine stellate ganglia

Annals of the New York Academy of Sciences, Volume 1545, Issue 1, Page 91-104, March 2025.
An investigation into the electrophysiological properties of murine ventricular myocardium and stellate ganglia was conducted using the loose patch clamp technique at two distinct age points to assess aging‐mediated alterations in ionic currents. The voltage‐gated inward sodium current, quantified as maximum sodium current (INa(Max)), was reduced with ...
Bonn Lee, Shiraz Ahmad, Charlotte E. Edling, Christopher L.‐H. Huang, Fiona E. N. LeBeau, Kamalan Jeevaratnam   +5 more
wiley   +1 more source