Results 241 to 250 of about 72,976 (300)

Galanin Receptors in the Central Nervous System: Exploring Ligand Interactions, Signal Transduction, and Potential Clinical Implications. [PDF]

Molecules
Owczarek A, Blecharz-Klin K.
europepmc   +1 more source

Heartfelt intervention: A role for PVN oxytocin neurons in the prediabetic heart

The Journal of Physiology, EarlyView.
Grace K. Nielsen, Reesa M. Wilcox, Han‐Jun Wang   +2 more
wiley   +1 more source

Neurotransmitters in tumors: chemical cross-talk shaping tumor progression. [PDF]

Biomark Res
Chen W, Yu J, Ge S, Yuan T, Ding X, Yan B, Ye L, Wang Y, Jia R.   +8 more
europepmc   +1 more source

Transcriptomic signatures in tetrapartite brain region identifies shared and unique gene signatures for substance-use. [PDF]

Front Cell Neurosci
Veerappa A, Guda C.
europepmc   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

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Neuropeptide Y receptor subtypes

Life Sciences, 1995
Neuropeptide Y (NPY) is an amidated 36-amino acid peptide with a wide distribution in the central and peripheral nervous system. It can evoke numerous physiological responses by activating specific receptors. Studies using NPY analogs in various model systems and cell types demonstrate different orders of ligand potency and receptor binding affinity ...
C P, Wan, B H, Lau
openaire   +2 more sources

Dihydropyridine Neuropeptide Y Y1 Receptor Antagonists

Bioorganic & Medicinal Chemistry Letters, 2002
Dihydropyridine 5a was found to be an inhibitor of neuropeptide Y(1) binding in a high throughput (125)I-PYY screening assay. Structure-activity studies around certain portions of the dihydropyridine chemotype identified BMS-193885 (6e) as a potent and selective Y(1) receptor antagonist.
Graham S, Poindexter, Marc A, Bruce, Karen L, LeBoulluec, Ivo, Monkovic, Scott W, Martin, Eric M, Parker, Larry G, Iben, Rachel T, McGovern, Astrid A, Ortiz, Jennifer A, Stanley, Gail K, Mattson, Michael, Kozlowski, Meredith, Arcuri, Ildiko, Antal-Zimanyi   +13 more
openaire   +2 more sources

Neuropeptide Y receptor antagonists in obesity

Expert Opinion on Investigational Drugs, 1997
Neuropeptide Y (NPY) is a 36 amino acid amidated peptide with high sequence homology to the endocrine peptides, peptide YY (PYY) and pancreatic polypeptide (PP). They appear to interact with a family of receptors that possess high affinity for one or more of these peptides.
D R, Gehlert, P A, Hipskind
openaire   +2 more sources

Neuropeptide Y receptors

2002
Abstract Neuropeptide Y (NPY) was isolated from porcine brain almost two decades ago (Tatemoto and Mutt 1980). This 36 amino acid residues shares high sequence homology and structural identity with two other peptides, namely peptide YY (PYY) and pancreatic polypeptide (PP) (Tatemoto et al . 1982).
Yvan Dumont, John Paul Redrobe, Rémi Quirion   +2 more
openaire   +1 more source