Neuropeptide y receptors - Open Access .click

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Effect of a selective neuropeptide Y Y2 receptor antagonist, BIIE0246 on neuropeptide Y release

European Journal of Pharmacology, 2000
We have examined the selective neuropeptide Y Y(2) receptor antagonist, (S)-N(2)-[[1-[2-[4-[(R,S)-5,11-dihydro-6(6h)-oxodibenz[b, e]azepin-11-yl]-1-piperazinyl]-2-oxoethyl]cyclopentyl]acetyl ]-N-[2-[1 ,2-dihydro-3,5(4H)-dioxo-1,2-diphenyl-3-H-1,2, 4-triazol-4-yl]ethyl]-argininamid (BIIE0246) on neuropeptide release from rat hypothalamic slices in vitro.
P J, King, G, Williams, H, Doods, P S, Widdowson +3 more
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Neuropeptide Y receptor antagonists.

IDrugs : the investigational drugs journal, 2005
A review of the patent literature for neuropeptide Y (NPY) antagonists is presented for the period of January 2000 to March 2001. This review focuses on antagonists of the Y(1) and Y(5) receptor subtypes, which have been of primary interest as anti-obesity agents.
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Neuropeptide Y (NPY) Y1 Receptor Antagonists

2001
Neuropeptide Y(NPY), a 36-residue peptide amide isolated originally from porcine brain, exhibits a wide spectrum of central and peripheral activities mediated by at least six receptor subtypes denoted as Y1, Y2, Y3, Y4, Y5 and Y6 [1]. Investigations to date have implicated NPY in the pathophysiology of a number of diseases including feeding disorders ...
V. C. Dhawan +6 more
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Neuropeptide Y receptors in pig spleen

Acta Physiologica Scandinavica, 1987
A, Härfstrand, J M, Lundberg, K, Fuxe
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Neuropeptide Y receptors

Trends in Pharmacological Sciences, 1993
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Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues