Results 81 to 90 of about 21,634,263 (295)
Neuropeptide y in sympathetic nerves — evidence for Y1 receptor mediated vascular control
, 1997 This chapter discusses the role of neuropeptide Y (NPY) in sympathetic neurotransmission and cardiovascular disorders. The release of transmitters—adenosine triphosphate (ATP), noradrenaline (NA), NPY—from sympathetic nerves is influenced by ...
Lundberg, JM +3 more
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Characterization of Neuropeptide S (NPS) in view of its potential as a novel anxiolytic therapy for anxiety disorders [PDF]
, 2012 Anxiety disorders, such as posttraumatic stress disorder (PTSD), are characterized by a high prevalence and debilitating symptoms. However, the current first-line treatment for these conditions, which consists of selective serotonin reuptake inhibitors ...
Ionescu, Irina
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American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun +7 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley +1 more source
NPY2R signaling gates spontaneous and mechanical, but not thermal, pain transmission
Molecular Pain, 2019 Neuropeptide Y signaling plays an important role in inhibiting chronic pain in the spinal cord of mice. However, little is known about the respective roles of two major neuropeptide Y receptors, Y1R and Y2R, in evoked and spontaneous pain behavior under ...
Sihan Chen +4 more
doaj +1 more source
Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients
Annals of Neurology, EarlyView.Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer +14 more
wiley +1 more source
Annals of Neurology, EarlyView.Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini +4 more
wiley +1 more source
Frontiers in EndocrinologyThe hypothalamus plays a central role in regulating metabolism by integrating neuropeptide signaling with environmental cues to maintain energy homeostasis.
Busayo Oladun, Smita Mall, Min-Hyun Kim
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The Role of Neuropeptide Y in Cardiovascular Health and Disease
Frontiers in Physiology, 2018 Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter, widely found in the central and peripheral nervous systems and with diverse roles in multiple physiological processes.
Cheryl M. J. Tan +5 more
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Neuropeptide Y and Y1 Receptors in Kindling Epileptogenesis [PDF]
Epilepsy Currents, 2004 Neuropeptide Y (NPY)-mediated neurotransmission undergoes plastic changes during hippocampal or amygdaloid kindling in rats as shown by changes in peptide cellular expression and distribution, its release and receptor subtype plasticity (for review see 37, 51). Electrophysiological and pharmacological evidence in in vitro and in vivo models of seizures
openaire +2 more sources