Results 141 to 150 of about 45,129 (213)

Influence of neurokinin B, dynorphin A and kisspeptin-10 on <i>in vitro</i> gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes. [PDF]

open access: yesJ Vet Res
Szysiak N   +7 more
europepmc   +1 more source

The human colon: Evidence for degenerative changes during aging and the physiological consequences

open access: yesNeurogastroenterology &Motility, EarlyView.
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley   +1 more source

Gastric and sacral electrical stimulation for motility disorders—A clinical perspective

open access: yesNeurogastroenterology &Motility, EarlyView.
Abstract Background Electrical stimulation of the gut has been investigated in recent decades with a view to treating various gastro‐intestinal motility disorders including, among others, gastric electrical stimulation to relieve nausea and vomiting associated with gastroparesis and sacral neuromodulation to treat fecal incontinence and/or constipation.
Charlotte Desprez   +2 more
wiley   +1 more source

Central mechanisms of emesis: A role for GDF15

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Nausea and emesis are ubiquitously reported medical conditions and often present as treatment side effects along with polymorbidities contributing to detrimental life‐threatening outcomes, such as poor nutrition, lower quality of life, and unfavorable patient prognosis.
Tito Borner   +2 more
wiley   +1 more source

Evidence‐based review and frontiers of migraine therapy

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Cyclic vomiting syndrome (CVS) is identified as one of the “episodic syndromes that may be associated with migraine,” along with benign paroxysmal torticollis, benign paroxysmal vertigo, and abdominal migraine. It has been proposed that CVS and migraine may share pathophysiologic mechanisms of hypothalamic activation and altered ...
Kaitlin A. Greene   +2 more
wiley   +1 more source

Pain persists in mice lacking both Substance P and CGRPα signaling. [PDF]

open access: yesElife
MacDonald DI   +5 more
europepmc   +1 more source

Endocannabinoid signaling in stress, nausea, and vomiting

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Classical antiemetics that target the serotonin system may not be effective in treating certain nausea and vomiting conditions like cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS). As a result, there is a need for better therapies to manage the symptoms of these disorders, including nausea, vomiting, and ...
Marieka V. DeVuono   +2 more
wiley   +1 more source

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