Results 151 to 160 of about 14,577 (178)
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Diabetes Research and Clinical Practice, 2010
Minor alleles of two SNPs in intron 9 of the NRP1 gene, which encodes neuropilin-1, were found to be associated with type 1 diabetes (T1D) in children. Neuropilin-1 peptides were confined to islets in human pancreas. This suggests neuropilins-1 could influence the development of some cases of T1D in children.
Noaman M, Hasan +5 more
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Minor alleles of two SNPs in intron 9 of the NRP1 gene, which encodes neuropilin-1, were found to be associated with type 1 diabetes (T1D) in children. Neuropilin-1 peptides were confined to islets in human pancreas. This suggests neuropilins-1 could influence the development of some cases of T1D in children.
Noaman M, Hasan +5 more
openaire +2 more sources
Anti-Cancer Agents in Medicinal Chemistry, 2020
Background:As involved in tumor angiogenesis, Neuropilin Receptor type-1 (NRP-1) serves as an attractive target for cancer molecular imaging and therapy. Widespread expression of NRP-1 in normal tissues may affect anti-NRP-1 antibody tumor uptake.Objective:To assess a novel anti-NRP-1 monoclonal antibody A6-11-26 biodistribution in NRP-1 positive tumor
Chao Ma +7 more
openaire +2 more sources
Background:As involved in tumor angiogenesis, Neuropilin Receptor type-1 (NRP-1) serves as an attractive target for cancer molecular imaging and therapy. Widespread expression of NRP-1 in normal tissues may affect anti-NRP-1 antibody tumor uptake.Objective:To assess a novel anti-NRP-1 monoclonal antibody A6-11-26 biodistribution in NRP-1 positive tumor
Chao Ma +7 more
openaire +2 more sources
Neuropilin-1 in Immune-Mediated Diseases
2017In recent years, it was realized that NP-1 is important for maintaining normal immune response homeostasis. It was found that NP-1 is highly expressed on both murine and human T regulatory cells (Tregs), thus increasing Treg cell properties, especially their contribution to the maintenance of self-tolerance [4].
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Isoforms of Neuropilin-2 Denote Unique Tumor-Associated Macrophages in Breast Cancer
Frontiers in Immunology, 2022Adrian Lee +2 more
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Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling
EMBO Journal, 2006Yulin Liao +2 more
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Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth
Journal of Experimental Medicine, 2012Tim Sparwasser +2 more
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Neuropilin-1 Mediates Collapsin-1/Semaphorin III Inhibition of Endothelial Cell Motility
Journal of Cell Biology, 1999M Klagsbrun +2 more
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VEGF/Neuropilin Signaling in Cancer Stem Cells
International Journal of Molecular Sciences, 2019Arthur Mercurio, Mercurio Arthur M
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