Results 191 to 200 of about 21,250,288 (213)

Characterization of a new alternatively spliced neuropilin-1 isoform

Angiogenesis, 2003
Neuropilin-1 (NP1) and neuropilin-2 (NP2) are receptors for semaphorins, which act as axonal chemorepellents, and for members of the vascular endothelial growth factor (VEGF) family of angiogenic growth factors. The NP1 and NP2 genes consist of 17 exons, and protein isoforms are expressed because of alternative transcript splicing.
Qi, Tao, Simone C, Spring, Bruce I, Terman   +2 more
openaire   +2 more sources

Small molecule inhibitors of the co-receptor neuropilin-1

Drug Discovery Today
Neuropilin-1 (NRP-1) is a multifunctional cell surface receptor that acts as a co-receptor for vascular endothelial growth factor (VEGF), semaphorins (SEMAs), and transforming growth factor β (TGF-β), and is widely involved in various physiological and pathological processes such as neural development, angiogenesis, and immune regulation.
Yu-Heng, Liu, Kang-Hui, Liang, Wen, Zhang, Guo-Wu, Rao, Quan, Zheng   +4 more
openaire   +2 more sources

Neuropilin-1 in Immune-Mediated Diseases

2017
In recent years, it was realized that NP-1 is important for maintaining normal immune response homeostasis. It was found that NP-1 is highly expressed on both murine and human T regulatory cells (Tregs), thus increasing Treg cell properties, especially their contribution to the maintenance of self-tolerance [4].
openaire   +1 more source

Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth

Journal of Experimental Medicine, 2012
Wiebke Hansen, Christian Stockmann, Tim Sparwasser   +2 more
exaly  

Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling

EMBO Journal, 2006
Yasunori Shintani, Hisakazu Kato, Yulin Liao   +2 more
exaly  

Neuropilin-1 Mediates Collapsin-1/Semaphorin III Inhibition of Endothelial Cell Motility

Journal of Cell Biology, 1999
Shay Soker, JOSÉ Luis Alonso, Jonathan A Raper   +2 more
exaly  

Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1–dependent ABL1 activation in endothelial cells

Journal of Experimental Medicine, 2014
Claudio Raimondi, Alessandro Fantin, Laura Denti   +2 more
exaly  

Neuropilin-1 (NRP)

2008
openaire   +1 more source

Discovery of semaphorin receptors, neuropilin and plexin, and their functions in neural development

Journal of Neurobiology, 2004
Hajime Fujisawa
exaly  

Vascular endothelial growth factor (VEGF) receptor neuropilin-1's distribution in astrocytic tumors

Apmis, 2004
H Laursen
exaly