Results 131 to 140 of about 123,545 (372)

Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin

Nature Communications, 2020
Erythropoietin (EPO), named after its role in hematopoiesis, is also expressed in mammalian brain. In clinical settings, recombinant EPO treatment has revealed a remarkable improvement of cognition, but underlying mechanisms have remained obscure.
Debia Wakhloo, F. Scharkowski, Yasmina Curto, Umer Javed Butt, V. Bansal, Agnes A. Steixner-Kumar, L. Wüstefeld, A. Rajput, Sahab Arinrad, Matthias R. Zillmann, Anna Seelbach, I. Hassouna, Katharina Schneider, Abdul Qadir Ibrahim, H. Werner, H. Martens, K. Miskowiak, S. Wojcik, Stefan Bonn, J. Nácher, K. Nave, H. Ehrenreich   +21 more
semanticscholar   +1 more source

Brain Activation During Passive and Volitional Pedaling After Stroke [PDF]

, 2019
Background: Prior work indicates that pedaling-related brain activation is lower in people with stroke than in controls. We asked whether this observation could be explained by between-group differences in volitional motor commands and pedaling ...
Cleland, Brice T., Schindler-Ivens, Sheila M.   +1 more
core   +1 more source

Testing rTMS-Induced Neuroplasticity: A Single Case Study of Focal Hand Dystonia [PDF]

, 2018
Focal hand dystonia in musicians is a neurological motor disorder in which aberrant plasticity is caused by excessive repetitive use. This work's purposes were to induce plasticity changes in a dystonic musician through five daily thirty-minute sessions ...
Betti, Sonia, Castiello, Umberto, Sartori, Luisa, Spoto, Andrea   +3 more
core   +2 more sources

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

Age-related alterations in the behavioral response to a novel environment in the African turquoise killifish (Nothobranchius furzeri)

Frontiers in Behavioral Neuroscience
The African turquoise killifish (Nothobranchius furzeri) has emerged as a popular model organism for neuroscience research in the last decade. One of the reasons for its popularity is its short lifespan for a vertebrate organism. However, little research
Valerie Mariën, Ilayda Piskin, Caroline Zandecki, Caroline Zandecki, Jolien Van houcke, Lutgarde Arckens, Lutgarde Arckens   +6 more
doaj   +1 more source

Preclinical discovery of duloxetine for the treatment of depression [PDF]

, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María, Elorza, Julián, Micó Segura, Juan Antonio, Perez-Caballero, Laura, Torres-Sanchez, Sonia   +4 more
core   +2 more sources

The Relationship Between Precuneus Thickness and Psychopathology in Adolescent Females With Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder with structural brain alterations; however, the roles of cortical surface area (CSA) and cortical thickness (CTh) during adolescence remain unclear. Building on frequent reports of gray matter reductions in the cingulate cortex and precuneus, this study assesses CSA, CTh, and ...
Irina Jarvers, Raphael Degmayr, Alexandra Otto, Ricarda Jacob, Wilhelm Malloni, Stephanie Kandsperger, Daniel Schleicher, Angelika Ecker, Isabel Wiesinger, Christina Wendl, Mark Greenlee, Romuald Brunner   +11 more
wiley   +1 more source

Semiology in spontaneous versus cortical stimulation‐induced seizures during SEEG: A within‐patient comparison study

Epilepsia Open, EarlyView.
Abstract Objective We aimed to study the concordance of seizure semiology in direct electrical stimulation‐induced seizures (SIS) compared to spontaneous seizures during stereoelectroencephalography (SEEG) and to report on patient‐level variables associated with habitual and atypical SIS.
Marai Mahizhnan, Stéphane Dufau, John Phamnguyen, Arash Kahrom, Donald Craig, Aileen McGonigal   +5 more
wiley   +1 more source

Neurodegeneration and contralateral α-synuclein induction after intracerebral α-synuclein injections in the anterior olfactory nucleus of a Parkinson’s disease A53T mouse model

Acta Neuropathologica Communications, 2019
Parkinson’s disease is characterized by a proteinopathy that includes aggregates of α-synuclein. A recent hypothesis proposes a prion-like spreading mechanism for this α-synucleinopathy.
Alicia Flores-Cuadrado, Daniel Saiz-Sanchez, Alicia Mohedano-Moriano, Alino Martinez-Marcos, Isabel Ubeda-Bañon   +4 more
doaj   +1 more source

Identifying Distinct Latent Profiles of Executive Functioning Among Adolescents and Adults With Anorexia Nervosa and Adolescent Healthy Controls

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Research suggests executive functioning (EF) inefficiencies contribute to anorexia nervosa (AN) onset and maintenance. Identifying EF subtypes in adolescents and adults with AN compared to healthy controls (HC) may provide insights into differences in illness severity, risk for prolonged illness, and highlight who could respond best ...
Jiana Schnabel, Marita Cooper, Kristin Stedal, Mark Rose, Betteke Maria van Noort, Deborah A. G. Drabick, Lauren B. Alloy, C. Alix Timko   +7 more
wiley   +1 more source