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Grafman, in this issue, discusses four forms of neuroplasticity that may account for development and recovery of functional neural networks in the human brain. These include homologous area adaptation, cross-modal reassignment, map extension, and compensatory masquerade. The following discussion focuses on these forms of neuroplasticity as they pertain
Cynthia K. Thompson
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Gut Microbiota and Neuroplasticity [PDF]
The accumulating evidence linking bacteria in the gut and neurons in the brain (the microbiota–gut–brain axis) has led to a paradigm shift in the neurosciences. Understanding the neurobiological mechanisms supporting the relevance of actions mediated by the gut microbiota for brain physiology and neuronal functioning is a key research area.
Julia Murciano-Brea+3 more
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Mitochondria and Neuroplasticity [PDF]
The production of neurons from neural progenitor cells, the growth of axons and dendrites and the formation and reorganization of synapses are examples of neuroplasticity. These processes are regulated by cell-autonomous and intercellular (paracrine and endocrine) programs that mediate responses of neural cells to environmental input.
Mark P. Mattson+3 more
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Intravenous ketamine is posited to rapidly reverse depression by rapidly enhancing neuroplasticity. In human patients, we quantified gray matter microstructural changes on a rapid (24-h) timescale within key regions where neuroplasticity enhancements ...
Jared M. Kopelman+12 more
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Genetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate.
Sverre Grødem+6 more
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Role of glia and extracellular matrix in controlling neuroplasticity in the central nervous system
Neuronal plasticity is critical for the maintenance and modulation of brain activity. Emerging evidence indicates that glial cells actively shape neuroplasticity, allowing for highly flexible regulation of synaptic transmission, neuronal excitability ...
E. Dzyubenko, D. Hermann
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Brain Stimulation and Neuroplasticity [PDF]
Electrical or magnetic stimulation methods for brain or nerve modulation have been widely known for centuries, beginning with the Atlantic torpedo fish for the treatment of headaches in ancient Greece, followed by Luigi Galvani’s experiments with frog legs in baroque Italy, and leading to the interventional use of brain stimulation methods across ...
Ulrich Palm+2 more
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Recent technological advances have been permitted to use high-density electroencephalography (hdEEG) for the estimation of functional connectivity and the mapping of resting-state networks (RSNs).
Gaia Amaranta Taberna+3 more
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Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]
Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
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Towards an understanding of psychedelic-induced neuroplasticity
Classic psychedelics, such as LSD, psilocybin, and the DMT-containing beverage ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly, clinical improvements can last for months or years after treatment.
Abigail E. Calder, G. Hasler
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