Results 11 to 20 of about 50,956 (198)

Neuroplasticity [PDF]

Journal of Communication Disorders, 2000
Grafman, in this issue, discusses four forms of neuroplasticity that may account for development and recovery of functional neural networks in the human brain. These include homologous area adaptation, cross-modal reassignment, map extension, and compensatory masquerade. The following discussion focuses on these forms of neuroplasticity as they pertain
Cynthia K. Thompson
openaire   +4 more sources

Heparan Sulfates Regulate Axonal Excitability and Context Generalization through Ca²⁺/Calmodulin-Dependent Protein Kinase II

Cells, 2023
Our previous studies demonstrated that enzymatic removal of highly sulfated heparan sulfates with heparinase 1 impaired axonal excitability and reduced expression of ankyrin G at the axon initial segments in the CA1 region of the hippocampus ex vivo ...
Inseon Song, Tatiana Kuznetsova, David Baidoe-Ansah, Hadi Mirzapourdelavar, Oleg Senkov, Hussam Hayani, Andrey Mironov, Rahul Kaushik, Michael Druzin, Staffan Johansson, Alexander Dityatev   +10 more
doaj   +1 more source

The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age

Communications Biology, 2022
An integrated analysis of GABA concentration, interhemispheric phase-based connectivity behavior and in healthy human participants revealed a task-specific association between GABA concentration and motor-cortical connectivity.
Kirstin-Friederike Heise, Laura Rueda-Delgado, Sima Chalavi, Bradley R. King, Thiago Santos Monteiro, Richard A. E. Edden, Dante Mantini, Stephan P. Swinnen   +7 more
doaj   +1 more source

Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3

Cells, 2022
Understanding changes in the expression of genes involved in regulating various components of the neural extracellular matrix (ECM) during aging can provide an insight into aging-associated decline in synaptic and cognitive functions.
David Baidoe-Ansah, Sadman Sakib, Shaobo Jia, Hadi Mirzapourdelavar, Luisa Strackeljan, Andre Fischer, Stepan Aleshin, Rahul Kaushik, Alexander Dityatev   +8 more
doaj   +1 more source

Astrogliosis and sexually dimorphic neurodegeneration and microgliosis in the olfactory bulb in Parkinson’s disease

npj Parkinson's Disease, 2021
Hyposmia is prodromal, and male sex is a risk marker for an enhanced likelihood ratio of Parkinson’s disease. The literature regarding olfactory bulb volume reduction is controversial, although the olfactory bulb has been largely reported as an early and
Alicia Flores-Cuadrado, Daniel Saiz-Sanchez, Alicia Mohedano-Moriano, Elena Lamas-Cenjor, Victor Leon-Olmo, Alino Martinez-Marcos, Isabel Ubeda-Bañon   +6 more
doaj   +1 more source

Neuroprotective effects of crude extracts, compounds, and isolated molecules obtained from plants in the central nervous system injuries: a systematic review

Frontiers in Neuroscience, 2023
The number of people with central nervous system (CNS) injuries increases worldwide and only a few therapies are used to mitigate neurological damage.
Maria Vitoria Nava Moura, Gabriel Mesquita da Conceição Bahia, Marcio Gonçalves Correa, Maíza Amanda Araujo Sarges, Thaís Alves Lobão, Erica Miranda Sanches, Karen R. H. Matos Oliveira, Anderson Manoel Herculano, Carlomagno Pacheco Bahia   +8 more
doaj   +1 more source

Identifying predictors for postoperative clinical outcome in lumbar spinal stenosis patients using smart-shoe technology

Journal of NeuroEngineering and Rehabilitation, 2017
Background Approximately 33% of the patients with lumbar spinal stenosis (LSS) who undergo surgery are not satisfied with their postoperative clinical outcomes.
Sunghoon I. Lee, Andrew Campion, Alex Huang, Eunjeong Park, Jordan H. Garst, Nima Jahanforouz, Marie Espinal, Tiffany Siero, Sophie Pollack, Marwa Afridi, Meelod Daneshvar, Saif Ghias, Majid Sarrafzadeh, Daniel C. Lu   +13 more
doaj   +1 more source

Ultrastructural Analysis of a Forming Embryonic Embodiment in the Adult Zebrafish Optic Tectum Surviving in Organotypic Culture

NeuroSci, 2022
It has been shown that adult zebrafish are capable of regenerating regions of the central nervous system (CNS) after insult. Unlike in higher-order vertebrates where damage to the CNS leads to glial scar formation and permanent functional deficits ...
Ricardo L. Peguero, Nicole A. Bell, Andras Bimbo-Szuhai, Kevin D. Roach, Zoltan L. Fulop, Christopher P. Corbo   +5 more
doaj   +1 more source

State and trait of finger tapping performance in multiple sclerosis

Scientific Reports, 2021
Finger tapping tests have been shown feasible to assess motor performance in multiple sclerosis (MS) and were observed to be strongly associated with the estimated clinical severity of the disease.
Philipp Gulde, Heike Vojta, Joachim Hermsdörfer, Peter Rieckmann   +3 more
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5-HTR2A and 5-HTR3A but not 5-HTR1A antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood

Molecular Brain, 2018
Visual cortical areas show enhanced tactile responses in blind individuals, resulting in improved behavioral performance. Induction of unilateral vision loss in adult mice, by monocular enucleation (ME), is a validated model for such cross-modal brain ...
Nathalie Lombaert, Maroussia Hennes, Sara Gilissen, Giel Schevenels, Laetitia Aerts, Ria Vanlaer, Lieve Geenen, Ann Van Eeckhaut, Ilse Smolders, Julie Nys, Lutgarde Arckens   +10 more
doaj   +1 more source