Results 191 to 200 of about 123,545 (372)

Integrating Iso-seq and RNA-seq data for the reannotation of the killifish telencephalon transcriptome

Scientific Data
The short-lived and rapidly aging African turquoise killifish, Nothobranchius furzeri GRZ is a unique model to study vertebrate aging. Current genomic and full-length transcriptomic sequencing lacks full gene annotations, resulting in poor mapping in ...
Rajagopal Ayana, Tatiana Krutikhina, Jolien Van houcke, Caroline Zandecki, Valerie Mariën, Gregory E. Maes, Eve Seuntjens, Lutgarde Arckens   +7 more
doaj   +1 more source

Exercise as a Promising Adjunct Treatment for Methamphetamine Addiction: Advances in Understanding Neuroplasticity and Clinical Applications [PDF]

Yongting Li, Xiaolong Chen, Tingting Wang, Wenjun Zou, Yong Tang, Z. Li   +5 more
openalex   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Increasing Neuroplasticity to Bolster Chronic Pain Treatment: A Role for Intermittent Fasting and Glucose Administration?

, 2016
Kimberly T. Sibille, Felix Bartsch, Divya Reddy, Roger B. Fillingim, Andreas Keil   +4 more
openalex   +1 more source

Hippocampal subfield differences in people with and without recreational ketamine use: Insights from multi‐modal neuroimaging

Addiction, EarlyView.
Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu, Chia‐Chun Hung, Marc N. Potenza, Kun‐Hsien Chou, Pei‐Lin Lee, Chu‐Chung Huang, Chiang‐Shan R. Li, Tony Szu‐Hsien Lee, Ching‐Po Lin   +8 more
wiley   +1 more source

Neural correlates of transfer of learning in motor coordination tasks: role of inhibitory and excitatory neurometabolites

Scientific Reports
We aimed to investigate transfer of learning, whereby previously acquired skills impact new task learning. While it has been debated whether such transfer may yield positive, negative, or no effects on performance, very little is known about the ...
Amirhossein Rasooli, Sima Chalavi, Hong Li, Caroline Seer, Hamed Zivari Adab, Dante Mantini, Stefan Sunaert, Mark Mikkelsen, Richard A. E. Edden, Stephan P. Swinnen   +9 more
doaj   +1 more source

Physiological Evidence Consistent with Reduced Neuroplasticity in Human Adolescents Born Preterm [PDF]

, 2012
Julia B. Pitcher, Alysha M. Riley, Sebastian Doeltgen, Lisa Kurylowicz, John C. Rothwell, Suzanne M. McAllister, Ashleigh E. Smith, Angela Clow, David J. Kennaway, Michael C. Ridding   +9 more
openalex   +1 more source

Differences and Commonalities of Electrical Stimulation Paradigms After Central Paralysis and Amputation

Artificial Organs, EarlyView.
Invasive and non‐invasive functional electrical stimulation (FES) is a well‐established method to partially restore function after paralysis and deliver sensory feedback after amputation. This work summarizes the current state‐of‐the‐art of FES for restoring function, supporting rehabilitation therapy, and assistive devices.
Thomas Stieglitz, Ines Bersch, Natalie Mrachacz‐Kersting, Cristian Pasluosta   +3 more
wiley   +1 more source

Neurophysiological Effect of Transcutaneous Electrical Spinal Cord Stimulation in Chronic Complete Spinal Cord Injury

Artificial Organs, EarlyView.
TESCS‐ABT induced neurophysiological changes in individuals with chronic complete SCI, however these did not consistently translate into functional improvements. These findings highlight the role of residual supraspinal connectivity and inform future research to optimise this neurotechnology for SCI rehabilitation and identify likely responders ...
E. L. McNicol, B. Osuagwu, M. Purcell, E. J. McCaughey, C. Lincoln, L. Cope, A. Vučković   +6 more
wiley   +1 more source

The Orthotic Effect of Functional Electrical Stimulation on Reactive Stepping for People With Incomplete Spinal Cord Injury

Artificial Organs, EarlyView.
This study evaluated the orthotic effect of functional electrical stimulation (FES) on reactive stepping in 16 participants with chronic, motor incomplete spinal cord injury (iSCI). Participants completed 10–20 trials of the Lean‐and‐Release test, with FES applied in half at random.
Matthew G. Heffernan, Jonguk Lee, Katherine Chan, Elizabeth L. Inness, Kei Masani, Kristin E. Musselman   +5 more
wiley   +1 more source