Results 61 to 70 of about 54,025 (256)

The Current Status of Somatostatin-Interneurons in Inhibitory Control of Brain Function and Plasticity

Neural Plasticity, 2016
The mammalian neocortex contains many distinct inhibitory neuronal populations to balance excitatory neurotransmission. A correct excitation/inhibition equilibrium is crucial for normal brain development, functioning, and controlling lifelong cortical ...
Isabelle Scheyltjens, Lutgarde Arckens
doaj   +1 more source

Experimental Pipeline (Expipe): A Lightweight Data Management Platform to Simplify the Steps From Experiment to Data Analysis

Frontiers in Neuroinformatics, 2020
As experimental neuroscience is moving toward more integrative approaches, with a variety of acquisition techniques covering multiple spatiotemporal scales, data management is becoming increasingly challenging for neuroscience laboratories.
Mikkel Elle Lepperød, Mikkel Elle Lepperød, Svenn-Arne Dragly, Svenn-Arne Dragly, Alessio Paolo Buccino, Alessio Paolo Buccino, Alessio Paolo Buccino, Milad Hobbi Mobarhan, Milad Hobbi Mobarhan, Anders Malthe-Sørenssen, Anders Malthe-Sørenssen, Torkel Hafting, Torkel Hafting, Marianne Fyhn, Marianne Fyhn   +14 more
doaj   +1 more source

Neuroplasticity in Parkinson’s disease

Journal of Neural Transmission
AbstractParkinson’s disease (PD) is the second most frequent neurodegenerative disorder, affecting millions of people and rapidly increasing over the last decades. Even though there is no intervention yet to stop the neurodegenerative pathology, many efficient treatment methods are available, including for patients with advanced PD.
Popescu, Bogdan Ovidiu, Batzu, Lucia, Ruiz, Pedro, Tulbă, Delia, Moro, Elena, Santens, Patrick   +5 more
openaire   +3 more sources

Interaction of FXTAS Family History and College Degree Attainment Predicts Trajectories of Cognitive and Motor Symptoms in FMR1 Premutation Carrier Women

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT The present longitudinal study focuses on FMR1 premutation carrier women during midlife and early old age (n = 115). Bringing together the genetic risk factor of a family history of FXTAS and the environmental protective factor of higher education, the goal of the study was to determine how these factors potentially interact to predict self ...
Jinkuk Hong, Leann Smith DaWalt, Jessica Klusek, Elizabeth M. Berry‐Kravis, Marsha Mailick   +4 more
wiley   +1 more source

Multipathway modulation of neuroinflammation and oxidative stress by hesperidin in a rat single prolonged stress model of post‐traumatic stress disorder

Animal Models and Experimental Medicine, EarlyView.
Single prolonged stress (SPS) induces post‐traumatic stress disorder (PTSD)‐like neuropathology characterized by oxidative stress, neuroinflammation, astrocytic reactivity, neuronal damage, and reduced neurotrophic support in the hippocampus, amygdala, and prefrontal cortex. Hesperidin counteracts these effects by attenuating lipid peroxidation and pro‐
Godson Emeka Anyanwu, Ogan Christopher Akanaku, Augustine Oviosun, Precious E. Ekwueme, Paul Anyiom Odey, Chima Paul Okechukwu Ugwu, Chinyere Nkemjika Anyanwu   +6 more
wiley   +1 more source

Speech Biomarkers for Quantifying Effects of Subthalamic Deep Brain Stimulation in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže, Mário Sousa, Vojtěch Illner, Adriana Jorge, Matilde Castelli, Ines Debove, Andreia D. Magalhães, Julia Waskönig, Lenard Lachenmayer, Joan Philipp Michelis, Gerd Tinkhauser, Deborah Amstutz, Marie Elise Maradan‐Gachet, Katrin Petermann, Claudio Pollo, Tobias Nef, Paul Krack, Jan Rusz   +17 more
wiley   +1 more source

Experimental Directory Structure (Exdir): An Alternative to HDF5 Without Introducing a New File Format

Frontiers in Neuroinformatics, 2018
Natural sciences generate an increasing amount of data in a wide range of formats developed by different research groups and commercial companies.
Svenn-Arne Dragly, Svenn-Arne Dragly, Milad Hobbi Mobarhan, Milad Hobbi Mobarhan, Mikkel E. Lepperød, Mikkel E. Lepperød, Simen Tennøe, Simen Tennøe, Marianne Fyhn, Marianne Fyhn, Torkel Hafting, Torkel Hafting, Anders Malthe-Sørenssen, Anders Malthe-Sørenssen   +13 more
doaj   +1 more source

Age Is an Effect Modifier of Thrombectomy Benefit in a Socioeconomically Vulnerable Stroke Population

Annals of Neurology, EarlyView.
Objective Randomized trials from high‐income countries have shown that endovascular treatment (EVT) yields similar benefits in elderly and non‐elderly patients with large vessel occlusion stroke (LVOS). However, evidence from low/middle‐income countries remains scarce.
Fabricio O. Lima, Francisco José de A. Mont'Alverne, Letícia C. Rebello, Daniel G. Abud, Gisele S. Silva, Michel E. Frudit, Mário B. Wagner, Jamary Oliveira‐Filho, Diogo C. Haussen, David S. Liebeskind, Octávio M. Pontes‐Neto, Norberto A.F. Frota, Guilherme Dabus, Gabriel R. de Freitas, Adson F. de Lucena, Jeffrey L. Saver, Raul G. Nogueira, Sheila C.O. Martins, for the RESILIENT Trial Investigators   +18 more
wiley   +1 more source

Induced Suppression of the Left Dorsolateral Prefrontal Cortex Favorably Changes Interhemispheric Communication During Bimanual Coordination in Older Adults–A Neuronavigated rTMS Study

Frontiers in Aging Neuroscience, 2020
Recent transcranial magnetic stimulation (TMS) research indicated that the ability of the dorsolateral prefrontal cortex (DLPFC) to disinhibit the contralateral primary motor cortex (M1) during motor preparation is an important predictor for bimanual ...
Stefanie Verstraelen, Kim van Dun, Julie Duque, Hakuei Fujiyama, Oron Levin, Stephan P. Swinnen, Stephan P. Swinnen, Koen Cuypers, Koen Cuypers, Raf L. J. Meesen, Raf L. J. Meesen   +10 more
doaj   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source