Results 111 to 120 of about 171,447 (234)

Effects of aging, hypertension and diabetes on the mouse brain and heart vasculomes

Neurobiology of Disease, 2019
The emerging concept of the vasculome suggests that microvessels contribute to function and dysfunction in every organ. In the brain, aging and comorbidities such as hypertension and diabetes significantly influence a wide variety of neurodegenerative ...
Shuzhen Guo, Wenjun Deng, Changhong Xing, Yiming Zhou, MingMing Ning, Eng H. Lo   +5 more
doaj  

Technical aspects of an impact acceleration traumatic brain injury rat model with potential suitability for both microdialysis and PtiO2 monitoring

, 2007
This report describes technical adaptations of a traumatic brain injury (TBI) model-largely inspired by Marmarou-in order to monitor microdialysis data and PtiO2 (brain tissue oxygen) before, during and after injury. We particularly focalize on our model
Bruno Palmier, Bullock, Emilie Carré, Emmanuel Cantais, Foda, Gentleman, Jean-Jacques Risso, Jean-Pierre Terrier, Kawaguchi, Marmarou, Michel Lonjon, Olivier Darbin, Paxinos, Piper, Povlishock, Schallert, Warner   +16 more
core   +1 more source

Mitochondria-Targeted Antioxidant Therapeutics for Traumatic Brain Injury

Antioxidants
Traumatic brain injury (TBI) is a major global health problem that affects both civilian and military populations worldwide. Post-injury acute, sub-acute, and chronic progression of secondary injury processes may contribute further to other ...
Hiren R. Modi, Sudeep Musyaju, Meaghan Ratcliffe, Deborah A. Shear, Anke H. Scultetus, Jignesh D. Pandya   +5 more
doaj   +1 more source

Indefatigable CA1 Sector Neuroprotection with Mild Hypothermia Induced 6 Hours after Severe Forebrain Ischemia in Rats [PDF]

, 1999
Frederick Colbourne, Hui Li, Alastair M. Buchan   +2 more
openalex   +1 more source

Neuroprotective effects of carnitinoid compounds in rodent cellular and in vivo models of mitochondrial complex I dysfunction [PDF]

, 2019
Rotenone-mediated mitochondrial complex I inhibition was used to model Parkinson’s disease-like syndrome in Lewis rats. Tyrosine hydroxylase immunolabeling demonstrated a decrease in the number of dopaminergic neurons as well as aberrant morphology in ...
Steliou, Kosta
core  

Safety and efficacy of ciprofol for general anesthesia induction in elderly patients undergoing lumbar surgery

Frontiers in Medicine
ObjectiveThis study aimed to evaluate the safety and efficacy of ciprofol for anesthesia induction in elderly patients undergoing lumbar surgery.MethodsSixty patients aged 65–80 years scheduled for elective lumbar surgery under general anesthesia were ...
Gang Yao, Gang Yao, Gang Yao, Gang Yao, Xiaochun Wei, Xiaochun Wei, Xiaochun Wei, Xiaochun Wei, Yu Zhong, Guofeng Liu, Yanzhuo Zhang, Yanzhuo Zhang, Yanzhuo Zhang, Yanhua Chen   +13 more
doaj   +1 more source

Neuroprotection of cultured foetal rat hippocampal cells against glucose deprivation: are GABAergic neurons less vulnerable or more sensitive to TCP protection? [PDF]

, 1999
Isabelle Chaudieu, Alain Privat
openalex   +1 more source

Neuroprotection: role of the antiglaucomatous treatment [PDF]

, 1999
M Virno, Luigi Pannarale
openalex   +1 more source

Intranasal delivery of mitochondria targeted neuroprotective compounds for traumatic brain injury: screening based on pharmacological and physiological properties

Journal of Translational Medicine
Targeting drugs to the mitochondrial level shows great promise for acute and chronic treatment of traumatic brain injury (TBI) in both military and civilian sectors.
Jignesh D. Pandya, Sudeep Musyaju, Hiren R. Modi, Starlyn L. Okada-Rising, Zachary S. Bailey, Anke H. Scultetus, Deborah A. Shear   +6 more
doaj   +1 more source

Room F, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Neuroprotection from Delayed Post-Ischemic Administration of a Metalloporphyrin Catalytic Antioxidant in the Rat [PDF]

, 2000
Georg B. Mackensen, Manisha Patel, James D. Crapo, Ines Batinić‐Haberle, David S. Warner   +4 more
openalex   +1 more source