Results 101 to 110 of about 177,883 (410)
Neuroprotection by Therapeutic Hypothermia
Frontiers in Neuroscience, 2019 Hypothermia therapy is an old and important method of neuroprotection. Until now, many neurological diseases such as stroke, traumatic brain injury, intracranial pressure elevation, subarachnoid hemorrhage, spinal cord injury, hepatic encephalopathy, and
Ying-jian Sun +3 more
semanticscholar +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Maximizing neuroprotection: where do we stand?
, 2012 Damien P KufflerInstitute of Neurobiology, University of Puerto Rico, San Juan, Puerto RicoAbstract: Brain and spinal cord traumas include blunt and penetrating trauma, disease, and required surgery.
Kuffler DP
core
, 2013 Delaying clinical disease onset would greatly reduce neurodegenerative disease burden, but the mechanisms influencing early preclinical progression are poorly understood.
Julien, Jean-Pierre +6 more
core +1 more source
Mechanism of neuroprotection by trehalose: controversy surrounding autophagy induction
Cell Death and Disease, 2018 Trehalose is a non-reducing disaccharide with two glucose molecules linked through an α, α-1,1-glucosidic bond. Trehalose has received attention for the past few decades for its role in neuroprotection especially in animal models of various ...
He‐Jin Lee, Y. Yoon, Seung-Jae Lee
semanticscholar +1 more source
Advanced Science, EarlyView.A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu +5 more
wiley +1 more source
Microglia and Stem-Cell Mediated Neuroprotection after Neonatal Hypoxia-Ischemia [PDF]
, 2021 Catherine Brégère +3 more
openalex +1 more source
The Role of Astrocytes in Neuroprotection after Brain Stroke: Potential in Cell Therapy
Frontiers in Molecular Neuroscience, 2017 Astrocytes are commonly involved in negative responses through their hyperreactivity and glial scar formation in excitotoxic and/or mechanical injuries.
Andrea Becerra-Calixto +1 more
semanticscholar +1 more source
Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Advanced Science, EarlyView.Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
GRP78 at the Centre of the Stage in Cancer and Neuroprotection
Frontiers in Neuroscience, 2017 The 78-kDa glucose-regulated protein GRP78, also known as BiP and HSP5a, is a multifunctional protein with activities far beyond its well-known role in the unfolded protein response (UPR) which is activated after endoplasmic reticulum (ER) stress in the ...
Caty Casas
semanticscholar +1 more source