Results 231 to 240 of about 132,339 (311)

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury

open access: yesNeuroprotection, EarlyView.
This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla   +8 more
wiley   +1 more source

Neuroimaging Findings and Risk Factors for Brain Injury in Foetuses Treated for Anaemia

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Characterize neuroimaging findings in foetuses with anaemia and identify associated risk factors. Methods Retrospective cohort study of pregnancies with foetal anaemia (defined as haemoglobin > 2 standard deviations below the gestational age mean) confirmed by foetal blood sampling (FBS) and treated with intrauterine transfusion (IUT)
Laurence Sophie Carmant   +6 more
wiley   +1 more source

Neuroprotective Effects of <i>Carica papaya</i> in Experimental Models of Neurodegeneration: A Comprehensive Review. [PDF]

open access: yesFood Sci Nutr
Hossan R   +9 more
europepmc   +1 more source

Atopic dermatitis and attention‐deficit/hyperactivity disorder comorbidity in children and adolescents: Epidemiology, mechanisms, and clinical management

open access: yesPediatric Investigation, EarlyView.
This review synthesizes epidemiological evidence linking atopic dermatitis to attention‐deficit/hyperactivity disorder in children, proposes an “inflammation‐itch‐neurobehavioral axis” integrating sleep disruption, neuroendocrine dysregulation, and emerging neuro‐immune circuits, and outlines multidisciplinary management strategies targeting both skin ...
Qingyang Zhao   +11 more
wiley   +1 more source

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