Results 241 to 250 of about 174,618 (333)

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Exploration of neuroprotective strategies in patients with acute promyelocytic leukemia complicated by cerebral hemorrhage. [PDF]

Front Med (Lausanne)
Hu J, Lai W.
europepmc   +1 more source

Selective Estrogen Receptor Modulator LY353381.HCl-Mediated Neuroprotection and BCL-2 Expression After Experimental Stroke [PDF]

, 2001
Mark I. Rossberg, Nabil J. Alkayed, Hung D Joh, Stephanie J. Murphy, Richard J Trastman, Patricia D. Hurn   +5 more
openalex   +1 more source

Exploring the Impact of a High‐Fat Diet on Brain Homeostasis: A Comprehensive Analysis of the Absence of Inflammation

Molecular Nutrition &Food Research, EarlyView.
Male and female mice were fed different diets for up to 24 weeks to study the effects of phytosterols (PS) on weight gain and brain immune cells. PS reduced weight gain in HFD‐fed mice. Microglia were isolated from brains and analyzed, revealing no diet‐driven inflammation changes, but differences based on sex and age.
Laura Plantera, Kerstin Immig, Anne‐Kristin Fritsche, Madlen Reinicke, Alon Zemer, Alon Monsonego, Uta Ceglarek, Ingo Bechmann   +7 more
wiley   +1 more source

Therapeutic Applications of Dental Mesenchymal Stem Cells in Alzheimer's Disease-A Scoping Review. [PDF]

Dent J (Basel)
Agnihotri R, Gaur S.
europepmc   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Perfusion-derived metrics to calculate cerebral infarct growth rate, "ultrafast progressor" phenotype, and neuroprotection. [PDF]

J Cereb Blood Flow Metab
Pensato U, Ospel JM.
europepmc   +1 more source

Older female mice lacking triggering recepter expressed on myeloid cells-2 have worse post-stroke neurological function and enhanced pro-inflammatory responses [PDF]

, 2019
Hsieh, C, Kacimi, R, Kurisu, K, Yenari, MA, Zheng, Z   +4 more
core  

Long-Term Performance and Safety of the Self-Expandable Carotid Stent MER: 5-Year Outcomes from the OCEANUS Study, with Subgroup Analysis Based on Predilatation Before Carotid Artery Stenting. [PDF]

J Clin Med
Nowakowski P, Sznapka M, Kobayashi A, Bil J, Paluszek P, Hrycek E, Nowakowska Z, Nowakowski M, Suchanek A, Pieniążek P.   +9 more
europepmc   +1 more source