Results 251 to 260 of about 174,618 (333)

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

open access: yesNeuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal   +2 more
wiley   +1 more source

The effects and mechanisms of stem cells and exosomes on neurological function protection and recovery after ischemic stroke

open access: yesNeuroprotection, EarlyView.
Effect and mechanism of stem cells and exosomes therapy in ischemic stroke. The effect and mechanism include protection of neuron and glial cells, repairment of nerve vascular unit, reduction of inflammation response, restoration of white matter integrity, reconstruction of neural circuit, replacement of neurons and glial cells, and anti‐ferroptosis ...
Weihong Du   +4 more
wiley   +1 more source

Neuroprotection by Intrathecal Application of Liposome-entrapped Fasudil in a Rat Model of Ischemia.

open access: gold, 2001
Yoshihiro Takanashi   +4 more
openalex   +2 more sources

A geriatrician's approach to managing the complex older adult with obesity

open access: yesObesity, EarlyView.
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley   +1 more source

Neuroprotective Efficacy of Microwave‐Assisted Synthetized 2‐(5‐Cyclopropyl‐6‐Thioxo‐1,3,5‐Thiadiazinan‐3‐Yl) Acetic Acid in Mitigating Cognitive Deficits in Pentylenetetrazole‐Induced Mice Model

open access: yesChemistryOpen, EarlyView.
Microwave synthesis yielded 2‐(5‐cyclopropyl‐6‐thioxo‐1,3,5‐thiadiazinan‐3‐yl)acetic acid, confirmed by infrared, nuclear magnetic resonance, and electron ionization mass spectrometry. In a pentylenetetrazole‐induced epilepsy model, it countered oxidative stress by boosting antioxidant enzymes (catalase, peroxidase, superoxide dismutase, glutathione ...
Tahir Iqbal   +9 more
wiley   +1 more source

Embelin Mitigates the Impact of Perinatal Inflammation on Neuron Development by Inhibiting 5‐Lipoxygenase‐Mediated Ferroptosis

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Neuronal development in newborns is often constrained by perinatal inflammation, with limited research available on the pathogenesis and treatment strategies for this condition. This study aimed to investigate the neuroprotective effects of Embelin in mitigating perinatal inflammation‐induced neuronal development limitations by targeting 5 ...
Feng Zhang   +6 more
wiley   +1 more source

Mechanically robust neuroprotective stent by sequential Mg ions release for ischemic stroke therapy. [PDF]

open access: yesNat Commun
Zhang H   +14 more
europepmc   +1 more source

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