Results 191 to 200 of about 114,586 (238)

Development of phytotherapeutic nanoformulation containing Gypsophila eriocalyx and its evaluation as a candidate formulation for osteoporosis treatment on human bone marrow stem cells

open access: yesPhytochemical Analysis, EarlyView.
Abstract Introduction Osteoporosis, one of the common bone diseases, manifests itself as a decrease in bone mass. Recently, the use of medicinal plants in the search for effective and low‐toxicity therapeutics for the prevention or treatment of osteoporosis has become a trending topic.
Sibel Kaymak   +6 more
wiley   +1 more source

Targeted Isolation of Coumarins From Sideritis Species Based on Antiviral Screening and Untargeted Metabolomics

open access: yesPhytochemical Analysis, EarlyView.
ABSTRACT Introduction The SARS‐CoV‐2 pandemic has revealed a deficiency in antiviral agents. Plants, traditionally used for respiratory infections, are valuable sources of antiviral compounds. Such a plant is the Sideritis L. taxa (mountain tea), traditionally used against cold and cough.
Ekaterina‐Michaela Tomou   +5 more
wiley   +1 more source

Docosahexaenoic acid ameliorates autistic‐like behaviors by inhibiting oxidative stress and inflammatory response in neonatal maternal separation rats

open access: yesPediatric Discovery, EarlyView.
The JNK pathway and oxidative stress are activated, and pro‐inflammatory cytokines are increased in neonatal maternal separation (NMS) rats. While docosahexaenoic acid treatment suppresses the activation of JNK pathway and oxidative stress, and reduces pro‐inflammatory cytokines release, thereby improving autism‐like behavior induced by NMS.
Boqing Xu   +5 more
wiley   +1 more source

Interactions of rare earth elements with living organisms and emerging biotechnical applications

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Rare earth elements (REEs) are critical resources required to achieve net‐zero carbon emission targets and energy security. However, rising demand for REEs coupled with significant extraction and processing challenges and geopolitical risks restricts access to REE resources.
Samantha A. McGaughey   +6 more
wiley   +1 more source

Treatment strategy for systemic lupus erythematosus using belimumab as indicated by multi‐omics analysis

open access: yesRheumatology &Autoimmunity, EarlyView.
Recent multi‐omics studies have demonstrated that belimumab specifically targets naïve B cells and a subset of memory B cells. This observation is consistent with belimumab's established efficacy and safety profile. Abstract Belimumab is an antibody targeting the cytokine B‐cell activating factor (BAFF), which is crucial for B cell differentiation, and
Keishi Fujio   +5 more
wiley   +1 more source

Biomimetic Robotics and Intelligence: A Survey

open access: yesSmartBot, EarlyView.
Biomimetic robotics and intelligence, inspired by biological systems, integrate biology, engineering, and AI, develops robots capable of adapting to complex environments. By mimicking natural structures and cognitive processes, and employing algorithms like neural networks and genetic algorithms, these systems enhance autonomy and problem‐solving. This
Yixuan Sheng   +6 more
wiley   +1 more source

NIR‐Induced Photoswitching Hybrid DNA Nanoconstruct‐Based Drug Delivery System for Spatiotemporal Control of Stem Cell Fate

open access: yesSmall, EarlyView.
NIR‐mediated photo‐switching drug delivery system for the remote‐control differentiation of NSCs. Left: NIR‐mediated curcumin release is induced by NIR‐to‐UV photon upconversion in a photo‐controllable manner. Curcumin is bound in the minor groove of the synthesized DNA construct containing AAP photo‐switchers. Right: The rational design of several AAP
Thanapat Pongkulapa   +8 more
wiley   +1 more source

Transforming Niclosamide through Nanotechnology: A Promising Approach for Long COVID Management

open access: yesSmall, EarlyView.
This review highlights the transformation of niclosamide, a repurposed drug, through molecular science strategies to overcome its pharmacokinetic limitations. Emphasizing novel nanohybrid technologies and delivery platforms, the article explores their therapeutic potential in targeting the complex pathophysiology of long COVID, paving the way for ...
Sanoj Rejinold N   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy