Results 51 to 60 of about 43,555 (263)

Autosomal recessive spastic ataxia of charlevoix-saguenay: Findings from MRI in two adult Italian siblings

Radiology Case Reports, 2020
Autosomal recessive spastic ataxia of Charlevoix-Saguenay is a rare neurodegenerative disorder caused by homozygous mutations in SACSgene. We present finding on MR imaging in 2 adult Italian siblings. According to the literature we have described same of
Maria Claudia Pensabene, MD, Milena Melis, MD, Laura De Corato, MD, Carla Di Stefano, MD, Giulia Pizzicannella, MD, Mariateresa Mondillo, MD, Andrea Amico, MD, Doriana Tatulli, MD, Roberto Floris, PhD.   +8 more
doaj   +1 more source

SOX9 Knockdown-Mediated FOXO3 Downregulation Confers Neuroprotection Against Ischemic Brain Injury

Frontiers in Cell and Developmental Biology, 2021
BackgroundEvidence exists uncovering that SRY-box transcription factor 9 (SOX9) plays a role in ischemic brain injury (IBI). Thus, the current study was conducted to elucidate the specific role of SOX9 and the mechanism by which SOX9 influenced IBI ...
Yiming Deng, Yiming Deng, Yiming Deng, Gaoting Ma, Gaoting Ma, Gaoting Ma, Feng Gao, Feng Gao, Feng Gao, Xuan Sun, Xuan Sun, Xuan Sun, Lian Liu, Lian Liu, Lian Liu, Dapeng Mo, Dapeng Mo, Dapeng Mo, Ning Ma, Ning Ma, Ning Ma, Ligang Song, Ligang Song, Ligang Song, Xiaochuan Huo, Xiaochuan Huo, Xiaochuan Huo, Hongwei He, Hongwei He, Hongwei He, Zhongrong Miao, Zhongrong Miao, Zhongrong Miao   +32 more
doaj   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht, Lukas Meyer, Gabriel Broocks, Matthias Bechstein, Christian Thaler, Christian Heitkamp, Laurens Winkelmeier, Vincent Geest, Alexander Heitkamp, Maximilian Jungnitz, Gregor Peter, Luca Meucci, Tobias Faizy, Jawed Nawabi, Caspar Brekenfeld, Fabian Flottmann, Maximilian Schell, Alexandros Hadjilaou, Uta Hanning, Götz Thomalla, Jens Fiehler, Susanne Gellißen, Helge C. Kniep, for the German Stroke Registry Endovascular Treatment, (GSR‐ET) Alexander Nave, Anna Alegiani, Annerose Mengel, Arno Reich, Bernd Eckert, Charlotte Pietrock, Christian Nolte, Eberhard Siebert, Fabian Flottmann, Fee Keil, Franziska Dorn, Gabor Petzold, Götz Thomalla, Hanna Zimmermann, Jan Borggrefe, Jan Hendrik Schäfer, Jens Fiehler, Joachim Röther, Klaus Gröschel, Lars Kellert, Mario Abruscato, Maximilian Schell, Omid Nikoubashman, Peter Schellinger, Silke Wunderlich, Steffen Tiedt, Sven Thonke, Timo Uphaus, Tobias Boeckh‐Behrens, Ulrike Ernemann   +53 more
wiley   +1 more source

Brain Injury Lesion Imaging Using Preconditioned Quantitative Susceptibility Mapping without Skull Stripping [PDF]

, 2018
BACKGROUND AND PURPOSE:Identifying cerebral microhemorrhage burden can aid in the diagnosis and management of traumatic brain injury, stroke, hypertension, and cerebral amyloid angiopathy.
Z. Liu, Liu, Z, A.J. Furst, M. Selim, Lee, B, K. Main, B. Lee, Spincemaille, P, Massaband, P, U. Nemec, M.M. Adamson, S.J. Holdsworth, P. Spincemallie, M. Moseley, Y. Wang, Soman, S, Main, K, Adamson, MM, Moseley, M, P. Massaband, Kolakowsky-Hayner, S, Nemec, U, Wang, Y, Selim, M, S. Kolakowsky-Hayner, G. Kim, Kim, G, Yesavage, J, S. Soman, J. Yesavage, Furst, AJ, Holdsworth, Samantha   +31 more
core   +1 more source

Brain MRI findings and their association with visual impairment in young adolescents born very preterm [PDF]

, 2023
Purpose Very preterm birth increases risk for neonatal white matter injury, but there is limited data on to what extent this persists into adolescence and how this relates to ophthalmological outcomes.
Kochukhova, Olga,, Larsson, Eva, Holmström, Gerd,, Fredriksson Kaul, Ylva, Hellström-Westas, Lena,, Holmström, Gerd, Kochukhova, Olga, Karimi, Annette, Lena Hellström-Westas, Hellström-Westas, Lena, Johansson, Martin, Johansson, Martin,, Eva Larsson, Wikström, Johan,, Montgomery, Cecilia, Montgomery, Cecilia,, Cecilia Montgomery, Wikström, Johan, Johan Wikström, Sirkku Setänen, Gerd Holmström, Ylva Fredriksson Kaul, Fredriksson Kaul, Ylva,, Annette Karimi, Olga Kochukhova, Martin Johansson, Setänen, Sirkku, Karimi, Annette,, Larsson, Eva,   +28 more
core   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Flat Detector CT with Cerebral Pooled Blood Volume Perfusion in the Angiography Suite: From Diagnostics to Treatment Monitoring

Diagnostics, 2022
C-arm flat-panel detector computed tomographic (CT) imaging in the angiography suite increasingly plays an important part during interventional neuroradiological procedures. In addition to conventional angiographic imaging of blood vessels, flat detector
Thijs van der Zijden, Annelies Mondelaers, Maurits Voormolen, Tomas Menovsky, Maarten Niekel, Thomas Jardinet, Thomas Van Thielen, Olivier D’Archambeau, Paul M. Parizel   +8 more
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Principles of diffusion tensor imaging and its application to neuroscience

Анналы клинической и экспериментальной неврологии, 2017
This review article deals with technical issues of diffusionweighted imaging (DWI), diffusion tensor imaging (DTI) andmagnetic resonance tractography. We define such parameters ofDWI like: apparent diffusion coefficient, b-factor, fractionalanisotropy ...
S. V. Kitaev, T. A. Popova
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source