Results 71 to 80 of about 7,284 (241)

The T‐Type Calcium Channel CACNA1H is Required for Smooth Muscle Cytoskeletal Organization During Tracheal Tubulogenesis

open access: yesAdvanced Science, Volume 11, Issue 44, November 26, 2024.
Defects in the T‐type calcium channel CACNA1H cause defects in airway smooth muscle formation and its cytoskeletal organization in tracheal stenosis, and pharmacological increase of RhoA activity can partially attenuate these defects in mice. Analysis of human tracheal tissues suggests that a decrease in CACNA1H proteins is associated with tracheal ...
Ziying Liu   +15 more
wiley   +1 more source

About a snail, a toad and rodents: animal models for adaptation research

open access: yesFrontiers in Endocrinology, 2010
Neural adaptation mechanisms have many similarities throughout the animal kingdom, enabling to study fundamentals of human adaptation in selected animal models with experimental approaches that are impossible to apply in man.
Eric W Roubos   +5 more
doaj   +1 more source

A multilayer network analysis of Alzheimer's disease pathogenesis: Roles for p‐tau, synaptic peptides, and physical activity

open access: yesAlzheimer's &Dementia, Volume 20, Issue 11, Page 8012-8027, November 2024.
Abstract INTRODUCTION In the aging brain, cognitive abilities emerge from the coordination of complex pathways arising from a balance between protective lifestyle and environmental factors and accumulation of neuropathologies. METHODS As part of the Rush Memory and Aging Project (n = 440), we measured accelerometer‐based actigraphy, cognitive ...
Andrea A. Jones   +9 more
wiley   +1 more source

High signal-to-noise imaging of spontaneous and 5 ns electric pulse-evoked Ca2+ signals in GCaMP6f-expressing adrenal chromaffin cells isolated from transgenic mice.

open access: yesPLoS ONE, 2023
In studies exploring the potential for nanosecond duration electric pulses to serve as a novel modality for neuromodulation, we found that a 5 ns pulse triggers an immediate rise in [Ca2+]i in isolated bovine adrenal chromaffin cells.
Ciara Viola   +5 more
doaj   +1 more source

Neurosecretion and sodium excretion

open access: yesKidney International, 1974
Over the last few years there has been an accumulation of observations which indicate that there is a humoral substance other than aldosterone which influences renal sodium excretion. The findings by numerous authors have demonstrated that this humoral factor increases the excretion of sodium in response to expansion of the extracellular fluid (ECF ...
Lee, Julius, deWardener, Hugh E.
openaire   +2 more sources

Neuroendocrine Neoplasms of the Breast: Current Insights and Future Directions

open access: yesCancer Reports, Volume 7, Issue 11, November 2024.
ABSTRACT Background The breast neuroendocrine neoplasms (NENs) represent a heterogeneous group of tumors and account for less than 1% of all NENs. The 5th edition of the WHO Classification of Breast Tumors in 2019 introduced a more stringent definition for breast NENs including neuroendocrine tumors (NETs) (G1, G2) and neuroendocrine carcinomas (NECs) (
Lei Jiang, Xinyuan Pan, Zhiqiang Lang
wiley   +1 more source

Physiological Function and Characterization of TRPCs in Neurons

open access: yesCells, 2014
Ca2+ entry is essential for regulating vital physiological functions in all neuronal cells. Although neurons are engaged in multiple modes of Ca2+ entry that regulates variety of neuronal functions, we will only discuss a subset of specialized Ca2 ...
Yuyang Sun   +3 more
doaj   +1 more source

Multi‐Organ Microphysiological Systems Targeting Specific Organs for Recapitulating Disease Phenotypes via Organ Crosstalk

open access: yesSmall Science, Volume 4, Issue 11, November 2024.
Multi‐organ microphysiological systems (MOMPS) replicate human microphysiology and interorgan crosstalk. The precise fabrication of MOMPS requires various elements, including biomaterials, cell sources, accurate organ crosstalk, biofabrication techniques, and humanized design.
Joeng Ju Kim   +2 more
wiley   +1 more source

Micromorphology of neurohypophysis of rats under experimental conditions [PDF]

open access: yes
The changes of the quantity of neurosecretory substance in neurohypophysis of rats under various experimental conditions are investigated. Comparing to the norm the quantity of neurosecretion after a long stay in the dark was larger. In animals subjected
Meitner, E. R., Proksova, E.
core   +1 more source

Home - About - Disclaimer - Privacy