Methylxanthines Modulate Circadian Period Length Independently of the Action of Phosphodiesterase
In Neurospora crassa, caffeine and other methylxanthines are known to inhibit phosphodiesterase (PDE) activity, leading to augmented cAMP levels. In this organism, it has also been shown that the addition of these drugs significantly lengthens the ...
Consuelo Olivares-Yañez+3 more
doaj +1 more source
Chitosan is a natural polymer with antimicrobial activity. Chitosan causes plasma membrane permeabilization and induction of intracellular reactive oxygen species (ROS) in Neurospora crassa. We have determined the transcriptional profile of N.
Federico López-Moya+5 more
semanticscholar +1 more source
The coding and noncoding transcriptome of Neurospora crassa
Background Long non protein coding RNAs (lncRNAs) have been identified in many different organisms and cell types. Emerging examples emphasize the biological importance of these RNA species but their regulation and functions remain poorly understood.
Ibrahim Avi Cemel+4 more
doaj +1 more source
Characterization of the temperature-sensitive mutations un-7 and png-1 in Neurospora crassa. [PDF]
The model filamentous fungus Neurospora crassa has been studied for over fifty years and many temperature-sensitive mutants have been generated. While most of these have been mapped genetically, many remain anonymous. The mutation in the N.
Michael G Dieterle+3 more
doaj +1 more source
The guanine nucleotide exchange factor RIC8 regulates conidial germination through Gα proteins in Neurospora crassa. [PDF]
Heterotrimeric G protein signaling is essential for normal hyphal growth in the filamentous fungus Neurospora crassa. We have previously demonstrated that the non-receptor guanine nucleotide exchange factor RIC8 acts upstream of the Gα proteins GNA-1 and
Borkovich, Katherine A+5 more
core +3 more sources
Efficient gene editing in Neurospora crassa with CRISPR technology
Efficient gene editing is a critical tool for investigating molecular mechanisms of cellular processes and engineering organisms for numerous purposes ranging from biotechnology to medicine.
T. Matsu-ura+3 more
semanticscholar +1 more source
Genetic architecture of a reinforced, postmating, reproductive isolation barrier between Neurospora species indicates evolution via natural selection. [PDF]
A role for natural selection in reinforcing premating barriers is recognized, but selection for reinforcement of postmating barriers remains controversial.
Elizabeth Turner+2 more
doaj +1 more source
Fungal endophyte misidentified as Neurospora crassa. [PDF]
The endophytic fungus isolate, ZP5SE, recently described in Rehman et al. 2008 was misidentified identified as Neurospora crassa. The 28S ribosomal gene sequence of the isolate shows 100% sequence similarity with GenBank accession Neurospora crassa ...
Qazi, G. N.+4 more
core +2 more sources
Bayesian Model Calibration and Sensitivity Analysis for Oscillating Biological Experiments [PDF]
Understanding the oscillating behaviors that govern organisms' internal biological processes requires interdisciplinary efforts combining both biological and computer experiments, as the latter can complement the former by simulating perturbed conditions with higher resolution.
arxiv
BackgroundLignocellulolytic fungal cells suffer endoplasmic reticulum (ER) stress during lignocellulase synthesis; however, an understanding of this integrated process on a genome-wide scale remains poor.
Feiyu Fan+6 more
semanticscholar +1 more source