Results 61 to 70 of about 46,863 (279)

Hypobranching Induced by Both Environmental Antioxidants and ROS Metabolism Gene Knockouts in Neurospora Crassa [PDF]

, 2015
Previous work suggested a role of reactive oxygen species (ROS) metabolism on branch density, the statistical distribution of physical distances between branch points along a growing hypha in Neurospora. Here we report the results of experiments designed
Abduljabar, Hamzah, Grashel, Tayler, Watters, Michael K, Yablonowski, Jacob   +3 more
core   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, Volume 600, Issue 6, Page 894-909, March 2026.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Mitochondrial protein import [PDF]

, 1988
Transport of nuclear-encoded precursor proteins into mitochondria includes proteolytic cleavage of aminoterminal targeting sequences in the mitochondrial matrix. We have isolated the processing activity from Neurospora crassa.
Hartl, Franz-Ulrich, Hawlitschek, Gerhard, Neupert, Walter, Schmidt, Bernd, Schneider, Helmut, Tropschug, Maximilian   +5 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, Volume 600, Issue 6, Page 847-861, March 2026.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, Volume 600, Issue 6, Page 765-792, March 2026.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Global Analysis of Predicted G Protein-Coupled Receptor Genes in the Filamentous Fungus, Neurospora crassa. [PDF]

, 2015
G protein-coupled receptors (GPCRs) regulate facets of growth, development, and environmental sensing in eukaryotes, including filamentous fungi. The largest predicted GPCR class in these organisms is the Pth11-related, with members similar to a protein ...
Ahrendt, Steven R, Barsoum, Andrew H, Borkovich, Katherine A, Cabrera, Ilva E, Cao, Jackie, Carrillo, Alexander J, Castillo, Ronald, Chen, Wan-Ching, Davidson, Liza M, Dinkchian, Alex, Guerrero, Nayeli, Kim, Stephanie, Kitada, Sho M, Krystofova, Svetlana, Lai, Taffani H, Li, Liande, Lim, Andrew, Mach, Ashley, Malekyan, Cristin, Michkov, Alexander V, Moua, Toua R, Pacentine, Itallia V, Servin, Jacqueline A, Torres, Carlos Rojas, Yamamoto, Alaina   +24 more
core  

Puromycin Sensitivity of Ribosomal Label after Incorporation of 14C-Labelled Amino Acids into Isolated Mitochondria from Neurospora crassa [PDF]

, 1969
Radioactive amino acids were incorporated into isolated mitochondria from Neurospora crassa. Then the mitochondrial ribosomes were isolated and submitted to density gradient centrifugation. A preferential labelling of polysomes was observed.
Dingman C. W., Dingman C. W., Kuntzel H., Kuntzel H., Luck D. J. L., Neupert W., Noll H., Peacock A. C., Rifkin M. R.   +8 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, Volume 600, Issue 6, Page 910-938, March 2026.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Circadian rhythm in succinate dehydrogenase activity in Neurospora crassa

Acta Biológica Colombiana, 2004
Neurospora crassa is a widely studied model of circadian rhythmicity. In this fungus, metabolism is controlled by multiple factors which include development, medium characteristics and the circadian clock. The study of the circadian control of metabolism
Claudia Patricia Álvarez Barón
doaj  

HDA-2-Containing Complex Is Required for Activation of Catalase-3 Expression in Neurospora crassa

mBio, 2022
It is essential for aerobic organisms to maintain the homeostasis of intracellular reactive oxygen species (ROS) for survival and adaptation to the environment.
Lingaonan He, Zeyu Duan, Muqun Yu, Shaohua Qi, Ying Wang, Huiqiang Lou, Qun He   +6 more
doaj   +1 more source