The FEBS Journal, EarlyView.Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova +5 more
wiley +1 more source
G Protein α Subunit Genes Control Growth, Development, and Pathogenicity of Magnaporthe grisea
Molecular Plant-Microbe Interactions, 1997 Three G protein α subunit genes have been cloned and characterized from Magnaporthe grisea: magA is very similar to CPG-2 of Cryphonectria parasitica; magB is virtually identical to CPG-1 of Cryphonectria parasitica, to gna1 of Neurospora crassa, and to ...
Shaohua Liu, Ralph A. Dean
doaj +1 more source
Experimental measurement of endocytosis in fungal hyphae. [PDF]
, 2018 The present study examines the notion that polarized exocytosis in the tips of growing hyphae creates an excess of plasma membrane and thus the need for its removal by endocytosis.
Bartnicki-Garcia, Salomon +3 more
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Fungi isolated from Miscanthus and sugarcane: biomass conversion, fungal enzymes, and hydrolysis of plant cell wall polymers. [PDF]
, 2015 BackgroundBiofuel use is one of many means of addressing global change caused by anthropogenic release of fossil fuel carbon dioxide into Earth's atmosphere.
Bauer, Stefan +6 more
core +2 more sources
H3K27me3‐Mediated Epigenetic Silencing of FgHMG1 Enables Fungal Host Immune Evasion
Plant Biotechnology Journal, EarlyView.ABSTRACT Histone H3 lysine 27 trimethylation (H3K27me3) is essential for fungal pathogenicity, yet its contribution to pathogen–host interactions remains incompletely understood. Here, we profiled H3K27me3 dynamics in Fusarium graminearum during infection and identified 132 H3K27me3‐marked genes (FgHMGs).
Xiaozhen Zhao +17 more
wiley +1 more source
Isolation and Characterization of Glycerol-3-Phosphate Dehydrogenase-Defective Mutants of \u3cem\u3eNeurospora crassa\u3c/em\u3e [PDF]
, 1978 Three glycerol-nonutilizing mutants deficient in the mitochondrial glycerol-3-phosphate (G3P) dehydrogenase (EC 1.1.99.5) were isolated from inlts derivatives of Neurospora crassa following inositolless death at elevated temperatures on minimal glycerol ...
Courtright, James B., Denor, Patrick F.
core +1 more source
Regulation of polarised growth in fungi [PDF]
, 2008 Polarised growth in fungi occurs through the delivery of secretory vesicles along tracks formed by cytoskeletal elements to specific sites on the cell surface where they dock with a multiprotein structure called the exocyst before fusing with the ...
Adamo +112 more
core +1 more source
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
FEBS Letters, Volume 600, Issue 1, Page 48-62, January 2026.The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
HDA-2-Containing Complex Is Required for Activation of Catalase-3 Expression in Neurospora crassa
mBio, 2022 It is essential for aerobic organisms to maintain the homeostasis of intracellular reactive oxygen species (ROS) for survival and adaptation to the environment.
Lingaonan He +6 more
doaj +1 more source
Cellular and extracellular siderophores of Aspergillus nidulans and Penicillium chrysogenum [PDF]
, 1981 Aspergillus nidulans and Penicillium chrysogenum produce specific cellular siderophores in addition to the well-known siderophores of the culture medium.
Charlang, Gisela +3 more
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