Results 41 to 50 of about 1,701,414 (246)

Continuum Robots in Surgery: From Engineering Design to Clinical Practice

Advanced Robotics Research, EarlyView.
The hyper‐redundant nature of continuum robot structures enables near‐infinite degrees of freedom leading to immense potential for medical applications. This review provides a historical background of continuum robots and novel ideas shaping their progress to current structural design, sensing technology, modeling techniques, and control methods.
Griffin Smith, Kaitlyn Clancy, Siwen Xie, Xiaochen Li, Sarah Khalife, Benjamin van der Woerd, Onaizah Onaizah   +6 more
wiley   +1 more source

New Insights into the Pharmacology of Dexmedetomidine and Open Issues for Neurosurgical Procedures

, 2020
Patients undergoing neurosurgical procedures or requiring mechanical ventilation at the end of the neurosurgical procedure need analgosedation to reduce the anxiety and discomfort related to the intervention, as well as to minimize ventilator intolerance
Scafuro M., Fiore M., Gargano F.
core   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Microneurorrhaphy of the mentonian nerve during the removal of a giant odontoma

RGO: Revista Gaúcha de Odontologia, 2019
The aim of this article is to describe a surgical technique of option in the treatment of large tumors in jaw whose risk of accidental rupture of the mental nerve presents increased by the report of a patient with mandibular giant case of odontoma.
André Lustosa SOUZA, Emerson Filipe de Carvalho NOGUEIRA, Paulo Alexandre da SILVA, Ricardo José de Holanda VASCONCELLOS, Airton Vieira Leite SEGUNDO   +4 more
doaj   +1 more source

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

Advanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil   +19 more
wiley   +1 more source

Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study [PDF]

, 2020
International audienceLimited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures.
Mills, Gary, Neto, Ary Serpa, Bluth, Thomas, Vidal Melo, Marcos, Canet, Jaume, Jaber, Samir, Hollmann, M. Wiersma, Schultz, Marcus, Putensen, Christian, Melo, Marcos F. Vidal, Serpa Neto, Ary, Schultz, Marcus J., Pelosi, Paolo, Hemmes, Sabrine, Ball, Lorenzo, Sales, G, Gama de Abreu, Marcelo, Hemmes, Sabrine N. T., FERS for the LAS VEGAS investigators, de Abreu, Marcelo Gama, Schmid, Werner, Robba, Chiara, Hollmann, M Wiersma, Vidal Melo, Marcos F., Battaglini, Denise, Hiesmayr, Michael, Wrigge, Hermann, Hemmes, Sabrine N.T., Brazzi, L, Severgnini, Paolo, Mills, Garty H., Mills, Gary H.   +31 more
core   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

Anaesthesia for neurosurgical procedures in paediatric patients

Indian Journal of Anaesthesia, 2012
Recent advances in neurosurgery, neuromonitoring and neurointensive care have dramatically improved the outcome in patients affected by surgical lesions of central nervous system (CNS).
Girija Prasad Rath, Hari H Dash
doaj   +1 more source

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice

Advanced Science, EarlyView.
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li, Hongzheng Lin, Sheng Yu, Yunhui Liao, Teng Huang, Zeyu Xiao, Wei Lu   +6 more
wiley   +1 more source

Gelatin-thrombin hemostatic matrix in neurosurgical procedures: hemostasis effectiveness and economic value of clinical and surgical procedure-related benefits

, 2020
BACKGROUND: Gelatin-thrombin hemostatic matrix (FloSeal®) use is associated with shorter surgical times and less blood loss, parameters that are highly valued in neurosurgical procedures.
Priola, Stefano M, Angileri, Filippo F, CAVALLO, LUIGI MARIA, Crimi, Salvatore, ESPOSITO, FELICE, CAPPABIANCA, PAOLO, Tomasello, Francesco, SOLARI, DOMENICO, Germanò, Antonino F, Cavallo, Luigi M, PRIOLA, STEFANO MARIA, GERMANO', Antonino Francesco, ANGILERI, Filippo, Solari D, Priola SM, Germanò AF, Cavallo LM, Crimi S, Angileri FF, Tomasello F, Esposito F, Cappabianca P   +21 more
core   +1 more source