Results 51 to 60 of about 1,701,414 (246)

Awake craniotomy:Part 2: Neurosurgical aspects

, 2006
Since October 2002 30 'awake craniotomy'-procedures were performed for brain tumour resection at the Erasmus Medical Centre in Rotterdam, The Netherlands.
Klimek, M.; id_orcid, Vincent, A. J.P.E.
core   +5 more sources

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

Clinicopathological study on refractory epilepsy treated by several epilepsy surgeries

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To observe and investigate the clinicopathological features and types of refractory epilepsy treated by several epilepsy surgeries. Methods There were 19 patients with age less than 20 years who underwent 2 (16/19) or 3 (3/19) epilepsy ...
Yan LI, Yong-ling LIU, Wei XING, Jing FU
doaj  

Risk index for perioperative atrial fibrillation in patients undergoing open intracranial neurosurgical procedures

, 2009
The aim of this prospective study was to determine the prevalence of pre-operative atrial fibrillation and the incidence of postoperative atrial fibrillation in patients undergoing elective or emergency intracranial neurosurgical procedures and the
F; Pizzichetta, F; Fiorani L; Paolini, F P; Delfini, Bilotta, R; Rosa G   +4 more
core   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Development and application of neurosurgery robots and navigation systems

Chinese Journal of Contemporary Neurology and Neurosurgery
The rapid development of neurosurgery robots and navigation systems has significantly enhanced surgical precision and safety. Neurosurgery robots, based on stereotactic technology, achieve submillimeter⁃level positioning through multi⁃modal image fusion ...
DING Hui, WANG Guang⁃zhi
doaj   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Clinical analysis of preoperative super-selective embolization in patients with large meningiomas

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
Nineteen cases of large meningiomas underwent microcatheter preoperative super-selective embolization before surgical resection. A total of 30 blood supply arteries underwent preoperative embolization, including total embolization (2 cases), most part
Chang-ji XIE, Zhi-yu ZHOU, Chun-zhen HUANG, Guang LI, Jian-rong HUANG, Guan-bin HUANG, Jie-fei CHEN, Cheng-cong WEI   +7 more
doaj  

Free rectus abdominis muscle flap for the treatment of complications after neurosurgical procedures

, 1996
Neurosurgical procedures may lead to mortal complications. Exposure of the dura mater, brain, or other intracranial structures; persistent cerebrospinal fluid fistulas; and connection between the extradural space and the nasopharynx and paranasal sinuses
Sanus, Z, Okur, I, Cansiz, H, Senyuva, C, Yucel, A   +4 more
core   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source