Results 11 to 20 of about 6,482 (150)

German guidelines on the diagnosis and treatment of neurosyphilis

Neurological Research and Practice, 2020
Introduction In view of the importance of neurosyphilis and the difficulties encountered in diagnosing it, the S1 guideline “Neurosyphilis” has been published by the German Society for Neurology (DGN) in accordance with the stipulations of the ...
Matthias Klein, Klemens Angstwurm, Stefan Esser, Kathrin Hahn, Matthias Maschke, Simone Scheithauer, Helmut Schoefer, Matthias Sturzenegger, Brigitte Wildemann, Jörg Weber   +9 more
doaj   +1 more source

An Updated Review of Recent Advances in Neurosyphilis

Frontiers in Medicine, 2022
Neurosyphilis is caused by Treponema pallidum invading the central nervous system, of which the incidence is increasing worldwide. Due to its variable clinical manifestations, diagnosis of neurosyphilis remains challenging, especially the asymptomatic ...
Jia Zhou, Jia Zhou, Hanlin Zhang, Hanlin Zhang, Keyun Tang, Keyun Tang, Runzhu Liu, Runzhu Liu, Jun Li, Jun Li   +9 more
doaj   +1 more source

Incidence of syphilitic hepatitis among patients with neurosyphilis. [PDF]

Intern Med J
Abstract Syphilis is a sexually transmitted infection of ongoing public health concern due to its systemic complications, which necessitate early detection and management. As a non‐hepatotropic pathogen, syphilis can also cause unexplained hepatitis, a condition that is often overlooked.
Sun J, Wang L, Pokorny C.
europepmc   +2 more sources

MRI of neurosyphilis with mesiotemporal lobe lesions of 'knife-cut sign' on MRI: A case report and literature review

Heliyon, 2023
Neurosyphilis with mesiotemporal lobe lesions remains a difficult entity to diagnose, especially when it mimics herpes simplex encephalitis (HSE). Here, we report what appeared to be the first case of mesiotemporal imaging of neurosyphilis presenting as ...
Hongwei Liu, Defu Dong
doaj   +1 more source

Regulatory T cells in peripheral blood and cerebrospinal fluid of syphilis patients with and without neurological involvement. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Syphilis, a sexually transmitted disease caused by spirochetal bacterium Treponema pallidum, can progress to affect the central nervous system, causing neurosyphilis.
Kang Li, Cuini Wang, Haikong Lu, Xin Gu, Zhifang Guan, Pingyu Zhou   +5 more
doaj   +1 more source

Asymptomatic Neurosyphilis Presenting With Bilateral Pulmonary Nodules: A Case Report. [PDF]

Respirol Case Rep
This report presents for the first time, a case of asymptomatic neurosyphilis with multiple pulmonary nodules and buttock lipodystrophy. This case showed a high expression of RPR (154 R.U.) and given the nature of the patient's work (long‐distance transportation), short‐term follow‐up was difficult.
Takahashi H, Ishida T.
europepmc   +2 more sources

Retrospective review of tertiary and neurosyphilis cases in Alberta, 1973–2017

BMJ Open, 2019
ObjectivesTo review the notification rate and characteristics of tertiary and neurosyphilis cases in Alberta, Canada in the postantibiotic era.MethodsA retrospective review of all neurosyphilis and tertiary syphilis cases reported in Alberta from 1973 to
Jennifer Gratrix, Petra Smyczek, Takaaki Landry, Ryan Cooper, Lindsay Bertholet, Ron Read, Barbara Romanowski   +6 more
doaj   +1 more source

Comparison of Treponema-specific immunoglobulin G (IgG) index with Treponema pallidum particle agglutination (TPPA) index for detection of intrathecal Treponema-specific antibody synthesis for serological diagnosis of neurosyphilis

GMS Infectious Diseases, 2023
The determination of -specific intrathecal immunoglobulin synthesis with the particle agglutination (TPPA) index is a well-established method recommended in German guidelines for the diagnosis of neurosyphilis.
Wellinghausen, Nele, Götz, Andrea, Rangel Vivar, Teresa Esthela   +2 more
doaj   +1 more source

Neurosyphilis: Concordance between cerebrospinal fluid analysis and subsequent antibiotic strategy for patients undergoing evaluation of a diagnosis of neurosyphilis

International Journal of Infectious Diseases, 2019
Introduction: The confirmation or analysis and exclusion of a diagnosis of neurosyphilis has long presented a challenge for infectious diseases clinicians. The authors reviewed the concordance between cerebrospinal fluid (CSF) analysis and the subsequent
O.C. Smibert, S. Abbinga, D.W. Spelman, A.W.J. Jenney   +3 more
doaj   +1 more source

The optimum condition of the toluidine red unheated serum test for the replacement of the venereal disease research laboratory test in cerebrospinal fluid for neurosyphilis diagnosis

Heliyon, 2023
Background: The cerebrospinal fluid (CSF) venereal disease research laboratory (VDRL) test remains the standard for the laboratory diagnosis of neurosyphilis.
Yao Xiao, Man-Li Tong, Yang Yang, Wei-Ming Gu, Li-Li Liu, Tian-Ci Yang   +5 more
doaj   +1 more source