Results 121 to 130 of about 25,999 (347)

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Plasma Exchange to Treat Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome after Anti-CD19 Chimeric Antigen Receptor-T Cell Infusion: A Case Report

, 2021
Yan Qiu, Wenjie Gong, Liqing Kang, Aining Sun, Depei Wu, Lei Yu, Jian Zhang, Shengli Xue   +7 more
openalex   +1 more source

Passado, presente e futuro da epilesia [PDF]

, 2007
Epilepsy is a complex brain disorder with diverse clinical features. Moreover, epilepsy is one of the most common serious neurological disorders worldwide with no age, racial, social class, national or geographic boundaries. This disease causes recurring
Aguire, Gisela, Funchal, Cláudia, McIntyre, Dan, Valles, Ana Sofia   +3 more
core  

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, EarlyView.
What's New? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Immune effector cell–associated neurotoxicity syndrome after chimeric antigen receptor T-cell therapy for lymphoma: predictive biomarkers and clinical outcomes [PDF]

, 2020
Noa G. Holtzman, Hao Xie, Søren M. Bentzen, Vivek Kesari, Ali Bukhari, Firas El Chaer, Forat Lutfi, Jonathan Siglin, Elizabeth Hutnick, Natalie Gahres, Kathleen Ruehle, Haroon Ahmad, Carl Shanholtz, Mehmet H. Kocoglu, Ashraf Badros, Jean A. Yared, Nancy M. Hardy, Aaron P. Rapoport, Saurabh Dahiya   +18 more
openalex   +1 more source

Management of neurotoxicity syndrome complicated by autologous hematopoietic stem cell transplantation bridge to chimeric antigen receptor T-Cell therapy: A case report [PDF]

, 2023
Pingfang Jiang, Pan Yang, Weijuan Wang, Jialei Cao, Wei Chen, Jianhong Fu, Lin Lu, Lu Yin, Xiaming Zhu   +8 more
openalex   +1 more source

Peripheral nerve hyperexcitability following titanium marker placement [PDF]

, 2020
Hill, Jeremy, Karwa, Karen, Li, Yuebing
core   +2 more sources

Things We Do for No Reason™: Prescribing gabapentinoids for pain

Journal of Hospital Medicine, EarlyView.
Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel, David Goese, Steven M. Belknap, Charles L. Madeira, Jeffrey H. Barsuk   +4 more
wiley   +1 more source

Neurotoxic implications of the agonistic action of CS‐syndrome pyrethroids on the N‐type Ca_v2.2 calcium channel [PDF]

, 2008
J. Marshall Clark, Steven B. Symington
openalex   +1 more source