Results 241 to 250 of about 90,679 (311)
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A Cycad Neurotoxin

2022
The cycads are a group of relict Mesozoic plants of which 10 genera now exist in the mainly tropical to warm temperate regions of the world. An additional toxicity which affects cattle after weeks of consumption of cycad leaves is a posterior ataxia known locally as “zamia staggers”. A toxin responsible for this condition has not so far been discovered.
Seawright, Alan A.   +3 more
openaire   +2 more sources

BIOLOGICAL NEUROTOXINS

Neurologic Clinics, 2000
The authors divide biological toxins into animal, plant, and bacterial classes and discuss each within a context of demographic, clinical and research examples. Advances in our knowledge are highlighted, and the authors relate the implications of this knowledge to target-specific neurologic involvement.
C G, Goetz, E, Meisel
openaire   +2 more sources

Alpha neurotoxins

Toxicon, 2013
α-Neurotoxins have been isolated from hydrophid, elapid and, more recently, colubrid snake venoms. Also referred to as postsynaptic neurotoxins or 'curare mimetic' neurotoxins, they play an important role in the capture and/or killing of prey by binding to the nicotinic acetylcholine receptor on the skeletal muscle disrupting neurotransmission.
Barber, Carmel M.   +2 more
openaire   +2 more sources

CLOSTRIDIAL NEUROTOXINS

Journal of Toxicology: Toxin Reviews, 2002
Tetanus (TeNT) and botulinum (BoNTs) neurotoxins are powerful toxins endowed with a specific zinc-endopeptidase activity. Targets of these neurotoxins have been identified as synaptic members of the SNARE proteins, which are involved in the exocytosis of neurotransmitters at the synapse.
Verastegui, C.   +4 more
openaire   +4 more sources

Selected Neurotoxins

Veterinary Clinics of North America: Small Animal Practice, 1988
The small animal practitioner is faced with an infinite number of potential toxins in our modern environment. Unapproved usage of drugs and insecticides requires the practitioner to keep informed about the development of new toxic syndromes. Recreational drug toxicosis in animals is still seen with some frequency in clinical practice and should not be ...
openaire   +2 more sources

Nonprotein Neurotoxins

Clinical Toxicology, 1981
Nonprotein neurotoxins are continuing to play a major role as molecular probes in studying nervous processes. They also have clinical importance as some of them, such as saxitoxin and its analogues, are the source of public health problems, or have potential use in therapy.
D J, Bower   +3 more
openaire   +2 more sources

Neurotoxins

2009
A selective neurotoxin takes many forms: as an antibody to a neurotrophin, as an alkylator, as an excitotoxin, as a blocker of requisite neuronal excitation during ontogenetic development, as a generator of oxidative stress, as an inhibitor of vital intraneuronal processes, and as an agent adversely affecting a host of multiple sites in neurons ...
openaire   +3 more sources

Proteomic insights into short neurotoxin-driven, highly neurotoxic venom of Philippine cobra (Naja philippinensis) and toxicity correlation of cobra envenomation in Asia.

Journal of Proteomics, 2019
The Philippine cobra, Naja philippinensis, is a WHO Category 1 venomous snake of medical importance responsible for fatal envenomation in the northern Philippines. To elucidate the venom proteome and pathophysiology of envenomation, N.
Choo Hock Tan   +4 more
semanticscholar   +1 more source

Recent progress in optical and electrochemical biosensors for sensing of Clostridium botulinum neurotoxin

Trends in Analytical Chemistry (TrAC), 2018
Botulinum toxin is a neurotoxic protein which produced from Clostridium botulinum and related species and it block acetylcholine release from presynaptic nerve terminals at the neuromuscular junctions.
Reza Eivazzadeh-Keihan   +7 more
semanticscholar   +1 more source

Neurotoxins Affecting Neuroexocytosis

Physiological Reviews, 2000
Nerve terminals are specific sites of action of a very large number of toxins produced by many different organisms. The mechanism of action of three groups of presynaptic neurotoxins that interfere directly with the process of neurotransmitter release is reviewed, whereas presynaptic neurotoxins acting on ion channels are not dealt with here.
SCHIAVO G.   +2 more
openaire   +4 more sources

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