Results 1 to 10 of about 3,194 (171)

Repeated onabotulinum neurotoxin A injections for drooling in children with neurodisability. [PDF]

Dev Med Child Neurol, 2021
Aim To evaluate the effect of repeated onabotulinum neurotoxin A injections for the treatment of drooling in children with neurodisabilities. Method This was a retrospective cohort study, in which the first, second, and third onabotulinum neurotoxin A injection were compared within children treated between 2000 and 2020.
Bekkers S, Leow TY, Van Hulst K, Orriëns LB, Scheffer AR, Van Den Hoogen FJ.   +5 more
europepmc   +2 more sources

Surgery versus botulinum neurotoxin A to reduce drooling and improve daily life for children with neurodevelopmental disabilities: a randomized controlled trial. [PDF]

Dev Med Child Neurol, 2021
Aim To compare the effect of bilateral submandibular duct ligation and botulinum neurotoxin A (BoNT‐A) on drooling severity and its impact on daily life and care in children and adolescents with moderate‐to‐severe drooling. Method This was a randomized, interventional, controlled trial in which 53 children and adolescents (31 males, 22 females, mean ...
Bekkers S, Pruijn IMJ, van der Burg JJW, van Hulst K, Kok SE, Delsing CP, Scheffer ART, van den Hoogen FJA.   +7 more
europepmc   +2 more sources

Pharmacological and neurosurgical interventions for individuals with cerebral palsy and dystonia: a systematic review update and meta-analysis. [PDF]

Dev Med Child Neurol, 2021
Aim To update a systematic review of evidence published up to December 2015 for pharmacological/neurosurgical interventions among individuals with cerebral palsy (CP) and dystonia. Method Searches were updated (January 2016 to May 2020) for oral baclofen, trihexyphenidyl, benzodiazepines, clonidine, gabapentin, levodopa, botulinum neurotoxin (BoNT ...
Bohn E, Goren K, Switzer L, Falck-Ytter Y, Fehlings D.   +4 more
europepmc   +2 more sources

Changes in severity and impact of drooling after submandibular gland botulinum neurotoxin A injections in children with neurodevelopmental disabilities. [PDF]

Dev Med Child Neurol, 2020
Aims To examine changes in objective and subjective drooling severity measures after submandibular botulinum neurotoxin A injection in children with neurodevelopmental disabilities, explore their relationship, and evaluate if clinically relevant responses relate to changes in the impact of drooling.
Van Hulst K, Van Der Burg JJ, Jongerius PH, Geurts AC, Erasmus CE.   +4 more
europepmc   +2 more sources

Efecto sobre el neurodesarrollo y neuroprotección en pez cebra de un extracto polifenólico de huesos de aceituna [PDF]

Nutrición Hospitalaria, 2014
Objetivo: Determinar el efecto de un extracto polifenólico de hueso de oliva en el desarrollo del sistema nervioso y frente al daño inducido mediante la neurotoxina ácido kaínico, utilizando como modelo animal el pez cebra. Material y métodos: Se analiza
Ernesto Cortés Castell, C. Veciana Galindo, L. Torro Montell, E. Sirvent Segura, M. M. Rizo Baeza, V. Gil Guillén   +5 more
doaj   +4 more sources

Botulinum toxin therapy in Parkinson disease-related lower limb dystonia. An 8 year retrospective review [PDF]

Clinical Parkinsonism & Related Disorders
Background: Lower extremity dystonia (LED) is a frequent complication of Parkinson disease (PD). Treatment with botulinum neurotoxinA (BoNTA) over 8 years was retrospectively reviewed.Cases14 patients with LED received an average of 3.86 injections (1–8).
Antonia Schonwald, Katherine Amodeo, Victoria Levy, Fabio Danisi   +3 more
doaj   +2 more sources

Neurotoxinas de invertebrados como alternativas terapéuticas y herramientas en investigación básica Neurotoxins from invertebrates as alternative therapeutic agents and tools in basic research

Vitae, 2009
Los venenos que producen los animales son una mezcla compleja de proteínas, péptidos, enzimas y trazas de elementos no proteicos tales como carbohidratos y sales, cuya finalidad es inmovilizar la presa y comenzar a digerirla.
Jaime A PEREAÑEZ, Leidy J VARGAS
doaj   +3 more sources

EFEITO PROLONGADO DA TOXINA BOTULÍNICA ASSOCIADA À SUPLEMENTAÇÃO COM ZINCO E FITASE

Arquivos de Ciências da Saúde da UNIPAR, 2023
A toxina botulínica é produzida naturalmente pela bactéria anaeróbia gram-positiva Clostridium botulinum, sendo considerada uma neurotoxina com efeitos capazes de reduzir atividades do sistema nervoso parassimpático, principalmente em relação as ...
Danniele Fernanda Eliseu Borges Viggiani, Dayane Kelly Sabec Pereira   +1 more
doaj   +1 more source

Coevolução molecular em canais iônicos e neurotoxinas [PDF]

, 2021
Dissertação (mestrado)—Universidade de Brasília, Programa de Pós-Graduação em Biologia Molecular, 2016. ; A peçonha de escorpiões contém diversos tipos de neurotoxinas que podem interagir entre si para modular a função de canais iônicos¹. A ação desses polipeptídeos leva à ativação de canais de sódio e inibição de canais de potássio, causando um ...
openaire   +2 more sources

Ação do acetilhexapeptídeo-3 no processo de rejuvenescimento facial [PDF]

Infarma: Pharmaceutical Sciences, 2018
O envelhecimento é um processo multifatorial, resultado de diversos fatores, intrínsecos e extrínsecos. Consiste em um processo continuo que não afeta apenas a aparência, mas as diversas estruturas e funções da pele.
Karina Elisa MACHADO, Geonara Leite SIGALES, Ivanisse SOLOVY   +2 more
doaj   +1 more source