Results 1 to 10 of about 224,377 (390)
Frontiers in Cellular Neuroscience, 2021 Neurotransmitter dynamics within neuronal synapses can be controlled by astrocytes and reflect key contributors to neuronal activity. In particular, Glutamate (Glu) released by activated neurons is predominantly removed from the synaptic space by ...
Bronac Flanagan +5 more
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Presynaptic Autophagy and the Connection With Neurotransmission
Frontiers in Cell and Developmental Biology, 2021 Autophagy is an evolutionary conserved catabolic pathway essential for the maintenance of cellular homeostasis. Defective proteins and organelles are engulfed by autophagosomal membranes which fuse with lysosomes for cargo degradation.
Marianna Decet +3 more
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Alzheimer’s Disease and Impaired Bone Microarchitecture, Regeneration and Potential Genetic Links
Life, 2023 Alzheimer’s Disease (AD) and osteoporosis are both age-related degenerative diseases. Many studies indicate that these two diseases share common pathogenesis mechanisms.
Min Zhang, Shunze Hu, Xuying Sun
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Targeted Sensors for Glutamatergic Neurotransmission [PDF]
Biophysical Journal, 2021 AbstractOptical report of neurotransmitter release allows visualization of excitatory synaptic transmission. Sensitive genetically-encoded glutamate reporters operating with a range of affinities and emission wavelengths are available. However, without targeting to synapses, the specificity of the fluorescent signal is uncertain, compared to sensors ...
Christian Rosenmund +6 more
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Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]
, 2013 The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre +3 more
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Frontiers in Neuroscience, 2021 Selenium (Se) and its compounds have been reported to have great potential in the prevention and treatment of Alzheimer’s disease (AD). However, little is known about the functional mechanism of Se in these processes, limiting its further clinical ...
Zhong-Hao Zhang +4 more
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Cell Reports, 2013 Expression of the human Parkinson-disease-associated protein α-synuclein in all Drosophila neurons induces progressive locomotor deficits. Here, we identify a group of 15 dopaminergic neurons per hemisphere in the anterior medial region of the brain ...
Thomas Riemensperger +8 more
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The role of neurosteroids in the pathogenesis of hepatic encephalopathy [PDF]
Medicinski Podmladak, 2016 Hepatic Encephalopathy (HE) represents a neuropsychiatric syndrome caused by acute or chronic liver failure. Hyperammonemia plays a pivotal role in the development of HE through modulation of neurotransmission, oxidative stress, neuroinflammation ...
Mladenović Dušan +2 more
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Measuring neuromuscular junction functionality [PDF]
, 2017 Neuromuscular junction (NMJ) functionality plays a pivotal role when studying diseases in which the communication between motor neuron and muscle is impaired, such as aging and amyotrophic lateral sclerosis (ALS).
Del Prete, Zaccaria +4 more
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