Results 1 to 10 of about 222,194 (391)

Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain

open access: yesFrontiers in Molecular Neuroscience, 2022
Opioids mediate their effects via opioid receptors: mu, delta, and kappa. At the neuronal level, opioid receptors are generally inhibitory, presynaptically reducing neurotransmitter release and postsynaptically hyperpolarizing neurons.
Kaitlin C. Reeves   +6 more
doaj   +2 more sources

The Role of Serotonin Neurotransmission in Gastrointestinal Tract and Pharmacotherapy

open access: yesMolecules, 2022
5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous system and peripheral structures, acting also as a hormone in platelets.
Tomasz Guzel, D. Mirowska-Guzel
semanticscholar   +1 more source

Autism Spectrum Disorder: Focus on Glutamatergic Neurotransmission

open access: yesInternational Journal of Molecular Sciences, 2022
Disturbances in the glutamatergic system have been increasingly documented in several neuropsychiatric disorders, including autism spectrum disorder (ASD).
M. Montanari   +3 more
semanticscholar   +1 more source

Memory Enhancement with Kynurenic Acid and Its Mechanisms in Neurotransmission

open access: yesBiomedicines, 2022
Kynurenic acid (KYNA) is an endogenous tryptophan (Trp) metabolite known to possess neuroprotective property. KYNA plays critical roles in nociception, neurodegeneration, and neuroinflammation.
Diána Martos   +4 more
semanticscholar   +1 more source

Adenosine Receptors in Neuropsychiatric Disorders: Fine Regulators of Neurotransmission and Potential Therapeutic Targets

open access: yesInternational Journal of Molecular Sciences, 2022
Adenosine exerts an important role in the modulation of central nervous system (CNS) activity. Through the interaction with four G-protein coupled receptor (GPCR) subtypes, adenosine subtly regulates neurotransmission, interfering with the dopaminergic ...
Silvia Pasquini   +6 more
semanticscholar   +1 more source

Dynamic control of the dopamine transporter in neurotransmission and homeostasis

open access: yesnpj Parkinson's Disease, 2021
The dopamine transporter (DAT) transports extracellular dopamine into the intracellular space contributing to the regulation of dopamine neurotransmission.
Mengfei Bu   +2 more
semanticscholar   +1 more source

Regulation of Melatonin and Neurotransmission in Alzheimer’s Disease

open access: yesInternational Journal of Molecular Sciences, 2021
Alzheimer’s disease is a neurodegenerative disorder associated with age, and is characterized by pathological markers such as amyloid-beta plaques and neurofibrillary tangles. Symptoms of AD include cognitive impairments, anxiety and depression.
Jaydeep Roy   +4 more
semanticscholar   +1 more source

Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission

open access: yesFrontiers in Synaptic Neuroscience, 2021
Synapses maintain synchronous, asynchronous, and spontaneous modes of neurotransmission through distinct molecular and biochemical pathways. Traditionally a single synapse was assumed to have a homogeneous organization of molecular components both at the
Natalie J. Guzikowski, E. Kavalali
semanticscholar   +1 more source

Presynaptic Autophagy and the Connection With Neurotransmission

open access: yesFrontiers in Cell and Developmental Biology, 2021
Autophagy is an evolutionary conserved catabolic pathway essential for the maintenance of cellular homeostasis. Defective proteins and organelles are engulfed by autophagosomal membranes which fuse with lysosomes for cargo degradation.
Marianna Decet   +3 more
doaj   +1 more source

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