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Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
Frontiers in Molecular Neuroscience, 2022 Opioids mediate their effects via opioid receptors: mu, delta, and kappa. At the neuronal level, opioid receptors are generally inhibitory, presynaptically reducing neurotransmitter release and postsynaptically hyperpolarizing neurons.
Kaitlin C. Reeves +3 more
semanticscholar +3 more sources
The Role of Serotonin Neurotransmission in Gastrointestinal Tract and Pharmacotherapy
Molecules, 2022 5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous system and peripheral structures, acting also as a hormone in platelets.
Tomasz Guzel, D. Mirowska-Guzel
semanticscholar +1 more source
Autism Spectrum Disorder: Focus on Glutamatergic Neurotransmission
International Journal of Molecular Sciences, 2022 Disturbances in the glutamatergic system have been increasingly documented in several neuropsychiatric disorders, including autism spectrum disorder (ASD).
M. Montanari +3 more
semanticscholar +1 more source
Memory Enhancement with Kynurenic Acid and Its Mechanisms in Neurotransmission
Biomedicines, 2022 Kynurenic acid (KYNA) is an endogenous tryptophan (Trp) metabolite known to possess neuroprotective property. KYNA plays critical roles in nociception, neurodegeneration, and neuroinflammation.
Diána Martos +4 more
semanticscholar +1 more source
Presynaptic Autophagy and the Connection With Neurotransmission
Frontiers in Cell and Developmental Biology, 2021 Autophagy is an evolutionary conserved catabolic pathway essential for the maintenance of cellular homeostasis. Defective proteins and organelles are engulfed by autophagosomal membranes which fuse with lysosomes for cargo degradation.
Marianna Decet +3 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 Neurotransmitter dynamics within neuronal synapses can be controlled by astrocytes and reflect key contributors to neuronal activity. In particular, Glutamate (Glu) released by activated neurons is predominantly removed from the synaptic space by ...
Bronac Flanagan +5 more
doaj +1 more source
Regulation of Melatonin and Neurotransmission in Alzheimer’s Disease
International Journal of Molecular Sciences, 2021 Alzheimer’s disease is a neurodegenerative disorder associated with age, and is characterized by pathological markers such as amyloid-beta plaques and neurofibrillary tangles. Symptoms of AD include cognitive impairments, anxiety and depression.
Jaydeep Roy +4 more
semanticscholar +1 more source
Food-derived Acetylcholinesterase Inhibitors as Potential Agents against Alzheimer’s Disease
eFood, 2021 Acetylcholinesterase (AChE) is a critical enzyme involved in nerve functions and signal transmission within the brain. However, during aging, excessive AChE activity often leads to rapid and progressive depletion of acetylcholine (ACh), the major ...
Rotimi E. Aluko
doaj +1 more source
Multilayer adaptive networks in neuronal processing [PDF]
The European Physical Journal Special Topics 227, 1039-1049 (2018), 2022 The connectome is a wiring diagram mapping all the neural connections in the brain. At the cellular level, it provides a map of the neurons and synapses within a part or all of the brain of an organism. In recent years, significant advances have been made in the study of the connectome via network science and graph theory.
arxiv +1 more source