Results 11 to 20 of about 138,388 (201)

Oméga 3 et neurotransmission cérébrale

open access: yesOléagineux, Corps gras, Lipides, 2004
Les acides gras polyinsaturés (AGPI) sont des constituants structuraux fondamentaux du système nerveux central (SNC) dont la teneur conditionne le fonctionnement des cellules neuronales. Ils sont des acteurs de la communication intercellulaire, notamment
Vancassel Sylvie
doaj   +2 more sources

Altered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants [PDF]

open access: yes, 2015
Alan L Pehrson, Connie Sanchez External Sourcing and Scientific Excellence, Lundbeck Research USA, Paramus, NJ, USA Abstract: Evidence suggesting that central nervous system γ-aminobutyric acid (GABA) concentrations are reduced in patients with ...
Sanchez C   +3 more
core   +1 more source

Impacts of Drugs on Neurotransmission [PDF]

open access: yes, 2022
The most sophisticated and mysterious human organ is the brain. The human brain is made up of billions of neurons, which are working nonstop to send and receive messages to regulate the body’s basic functions.
He, Wenrong
core   +1 more source

The GABA-Withdrawal Syndrome: A Model of Local Status Epilepticus

open access: yesNeural Plasticity, 2000
The GABA-withdrawal syndrome (GWS) is a model of local status epilepticus following the interruption of a chronic GABA infusion into the rat somatomotor cortex.
Carmen Silva-Barrat   +2 more
doaj   +1 more source

Differential Myosin 5a splice variants in innervation of pelvic organs

open access: yesFrontiers in Physiology, 2023
Introduction: Myosin proteins interact with filamentous actin and translate the chemical energy generated by ATP hydrolysis into a wide variety of mechanical functions in all cell types. The classic function of conventional myosins is mediation of muscle
Josephine A. Carew   +10 more
doaj   +1 more source

Membrane Fusion Involved in Neurotransmission: Glimpse from Electron Microscope and Molecular Simulation

open access: yesFrontiers in Molecular Neuroscience, 2017
Membrane fusion is one of the most fundamental physiological processes in eukaryotes for triggering the fusion of lipid and content, as well as the neurotransmission.
Zhiwei Yang   +7 more
doaj   +1 more source

A Role for the V0 Sector of the V-ATPase in Neuroexocytosis: Exogenous V0d Blocks Complexin and SNARE Interactions with V0c

open access: yesCells, 2023
V-ATPase is an important factor in synaptic vesicle acidification and is implicated in synaptic transmission. Rotation in the extra-membranous V1 sector drives proton transfer through the membrane-embedded multi-subunit V0 sector of the V-ATPase.
Christian Lévêque   +11 more
doaj   +1 more source

A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice

open access: yesEMBO Molecular Medicine, 2018
Normal hearing and synaptic transmission at afferent auditory inner hair cell (IHC) synapses require otoferlin. Deafness DFNB9, caused by mutations in the OTOF gene encoding otoferlin, might be treated by transferring wild‐type otoferlin cDNA into IHCs ...
Hanan Al‐Moyed   +5 more
doaj   +1 more source

The role of neurosteroids in the pathogenesis of hepatic encephalopathy [PDF]

open access: yesMedicinski Podmladak, 2016
Hepatic Encephalopathy (HE) represents a neuropsychiatric syndrome caused by acute or chronic liver failure. Hyperammonemia plays a pivotal role in the development of HE through modulation of neurotransmission, oxidative stress, neuroinflammation ...
Mladenović Dušan   +2 more
doaj   +1 more source

Neuronal epigenetics and the aging synapse

open access: yesFrontiers in Cellular Neuroscience, 2015
Two of the most salient phenotypes of aging are cognitive decline and loss of motor function, both of which are controlled by the nervous system. Cognition and muscle contraction require that neuronal synapses develop and maintain proper structure and ...
Benjamin A Eaton, Jorge eAzpurua
doaj   +1 more source

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